[HTML][HTML] Emerging roles of miR-145 in gastrointestinal cancers: A new paradigm
Gastrointestinal (GI) carcinomas are a group of cancers affecting the GI tract and digestive
organs, such as the gastric, liver, bile ducts, pancreas, small intestine, esophagus, colon …
organs, such as the gastric, liver, bile ducts, pancreas, small intestine, esophagus, colon …
[HTML][HTML] Current advancements and future perspectives of long noncoding RNAs in lipid metabolism and signaling
Background The investigation of lncRNAs has provided a novel perspective for elucidating
mechanisms underlying diverse physiological and pathological processes. Compelling …
mechanisms underlying diverse physiological and pathological processes. Compelling …
Insulin-like growth factor 2 mRNA-binding protein 2-stabilized long non-coding RNA Taurine up-regulated gene 1 (TUG1) promotes cisplatin-resistance of colorectal …
C Xia, Q Li, X Cheng, T Wu, P Gao, Y Gu - Bioengineered, 2022 - Taylor & Francis
Long non-coding RNAs (lncRNAs) have been demonstrated to influence the
chemoresistance of colorectal cancer (CRC). Therefore, the study is designed to investigate …
chemoresistance of colorectal cancer (CRC). Therefore, the study is designed to investigate …
[HTML][HTML] Role of long noncoding RNA taurine‐upregulated gene 1 in cancers
M Da, J Zhuang, Y Zhou, Q Qi, S Han - Molecular Medicine, 2021 - Springer
Long non-coding RNAs (lncRNAs) are a group of non-protein coding RNAs with a length of
more than 200 bp. The lncRNA taurine up-regulated gene 1 (TUG1) is abnormally …
more than 200 bp. The lncRNA taurine up-regulated gene 1 (TUG1) is abnormally …
[HTML][HTML] MicroRNAs and 'sponging'competitive endogenous RNAs dysregulated in colorectal cancer: Potential as noninvasive biomarkers and therapeutic targets
BG Jorgensen, S Ro - International Journal of Molecular Sciences, 2022 - mdpi.com
The gastrointestinal (GI) tract in mammals is comprised of dozens of cell types with varied
functions, structures, and histological locations that respond in a myriad of ways to …
functions, structures, and histological locations that respond in a myriad of ways to …
lncRNA TUG1 facilitates colorectal cancer stem cell characteristics and chemoresistance by enhancing GATA6 protein stability
J Sun, H Zhou, X Bao, Y Wu, H Jia… - Stem cells …, 2021 - Wiley Online Library
Background. Chemoresistance and tumor recurrence lead to high deaths in colorectal
cancer (CRC) patients. Cancer stem cells (CSCs) contribute to these pathologic properties …
cancer (CRC) patients. Cancer stem cells (CSCs) contribute to these pathologic properties …
P-MSC-derived extracellular vesicles facilitate diabetic wound healing via miR-145-5p/CDKN1A-mediated functional improvements of high glucose-induced …
J Su, Q Wei, K Ma, Y Wang, W Hu, H Meng, Q Li… - Burns & …, 2023 - academic.oup.com
Background Persistent hyperglycaemia in diabetes causes functional abnormalities of
human dermal fibroblasts (HDFs), partially leading to delayed skin wound healing …
human dermal fibroblasts (HDFs), partially leading to delayed skin wound healing …
LncRNA HCG18 promotes M2 macrophage polarization to accelerate cetuximab resistance in colorectal cancer through regulating miR-365a-3p/FOXO1/CSF-1 axis
C Gao, W Hu, J Zhao, X Ni, Y Xu - Pathology-Research and Practice, 2022 - Elsevier
Background Cetuximab (CET) resistance in colorectal cancer (CRC) is responsible to poor
prognosis to some extent. M2 macrophage polarization is closely correlated with drug …
prognosis to some extent. M2 macrophage polarization is closely correlated with drug …
Competitive endogenous RNA networks: Decoding the role of long non‐coding RNAs and circular RNAs in colorectal cancer chemoresistance
A Khalafizadeh, SD Hashemizadegan… - Journal of Cellular …, 2024 - Wiley Online Library
Colorectal cancer (CRC) is recognized as one of the most common gastrointestinal
malignancies across the globe. Despite significant progress in designing novel treatments …
malignancies across the globe. Despite significant progress in designing novel treatments …
[HTML][HTML] Role of TRP channels in carcinogenesis and metastasis: Pathophysiology and regulation by non-coding RNAs
A Turgambayeva, S Duisekova, G Tashenova… - Non-coding RNA …, 2023 - Elsevier
Abstract In 2021, David Julius and Ardem Patapoutian received Nobel Prize in Physiology or
Medicine for their ground-breaking discoveries in the functional characterization of receptors …
Medicine for their ground-breaking discoveries in the functional characterization of receptors …