The role of neuroinflammation in postoperative cognitive dysfunction: moving from hypothesis to treatment
SA Safavynia, PA Goldstein - Frontiers in psychiatry, 2019 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is a common complication of the surgical
experience and is common in the elderly and patients with preexisting neurocognitive …
experience and is common in the elderly and patients with preexisting neurocognitive …
Frailty adversely affects outcomes of patients undergoing spine surgery: a systematic review
V Chan, JRF Wilson, R Ravinsky, JH Badhiwala… - The Spine Journal, 2021 - Elsevier
Background With an aging population, there are an increasing number of elderly patients
undergoing spine surgery. Recent literature in other surgical specialties suggest frailty to be …
undergoing spine surgery. Recent literature in other surgical specialties suggest frailty to be …
[HTML][HTML] The impact of frailty on spine surgery: systematic review on 10 years clinical studies
F Veronesi, V Borsari, L Martini, A Visani… - Aging and …, 2021 - ncbi.nlm.nih.gov
Frailty is a condition characterized by a high vulnerability to low-power stressor. Frailty
increases with age and is associated with higher complications and mortality. Several …
increases with age and is associated with higher complications and mortality. Several …
Sarcopenia predicts perioperative adverse events following complex revision surgery for the thoracolumbar spine
Abstract Background Context Sarcopenia measured by psoas muscle index (PMI) has been
shown to predict perioperative mortality and adverse events (AEs) after various surgical …
shown to predict perioperative mortality and adverse events (AEs) after various surgical …
The 5-factor modified frailty index (mFI-5) is predictive of 30-day postoperative complications and readmission in patients with adult spinal deformity (ASD)
Background There is limited research regarding the association between the mFI-5 and
postoperative complications among adult spinal deformity (ASD) patients. Methods Using …
postoperative complications among adult spinal deformity (ASD) patients. Methods Using …
Frailty and sarcopenia: impact on outcomes following elective degenerative lumbar spine surgery
Study Design. This is a retrospective review of prospectively collected data. Objective. The
aim was to evaluate the impact of frailty and sarcopenia on outcomes after lumbar spine …
aim was to evaluate the impact of frailty and sarcopenia on outcomes after lumbar spine …
Evaluating frailty, mortality, and complications associated with metastatic spine tumor surgery using machine learning–derived body composition analysis
OBJECTIVE Cancer patients with spinal metastases may undergo surgery without clear
assessments of prognosis, thereby impacting the optimal palliative strategy. Because the …
assessments of prognosis, thereby impacting the optimal palliative strategy. Because the …
Paraspinal sarcopenia is associated with worse patient-reported outcomes following laminoplasty for degenerative cervical myelopathy
ZW Pinter, R Reed, SE Townsley, AL Mikula… - Spine, 2023 - journals.lww.com
Study Design. Retrospective cohort study. Objective. The present study is the first to assess
the impact of paraspinal sarcopenia on patient-reported outcome measures (PROMs) …
the impact of paraspinal sarcopenia on patient-reported outcome measures (PROMs) …
Systemic considerations for the surgical treatment of spinal metastatic disease: a scoping literature review
MA MacLean, CJ Touchette, M Georgiopoulos… - The Lancet …, 2022 - thelancet.com
Systemic assessment is a pillar in the neurological, oncological, mechanical, and systemic
(NOMS) decision-making framework for the treatment of patients with spinal metastatic …
(NOMS) decision-making framework for the treatment of patients with spinal metastatic …
In-hospital mortality for the elderly with acute traumatic spinal cord injury
T Inglis, D Banaszek, CS Rivers, D Kurban… - Journal of …, 2020 - liebertpub.com
As the incidence of traumatic spinal cord injury (tSCI) in the elderly rises, clinicians are
increasingly faced with difficult discussions regarding aggressiveness of management …
increasingly faced with difficult discussions regarding aggressiveness of management …