The role of neuroinflammation in postoperative cognitive dysfunction: moving from hypothesis to treatment

SA Safavynia, PA Goldstein - Frontiers in psychiatry, 2019 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is a common complication of the surgical
experience and is common in the elderly and patients with preexisting neurocognitive …

Frailty adversely affects outcomes of patients undergoing spine surgery: a systematic review

V Chan, JRF Wilson, R Ravinsky, JH Badhiwala… - The Spine Journal, 2021 - Elsevier
Background With an aging population, there are an increasing number of elderly patients
undergoing spine surgery. Recent literature in other surgical specialties suggest frailty to be …

[HTML][HTML] The impact of frailty on spine surgery: systematic review on 10 years clinical studies

F Veronesi, V Borsari, L Martini, A Visani… - Aging and …, 2021 - ncbi.nlm.nih.gov
Frailty is a condition characterized by a high vulnerability to low-power stressor. Frailty
increases with age and is associated with higher complications and mortality. Several …

Sarcopenia predicts perioperative adverse events following complex revision surgery for the thoracolumbar spine

T Hirase, V Haghshenas, R Bratescu, D Dong, PH Kuo… - The Spine Journal, 2021 - Elsevier
Abstract Background Context Sarcopenia measured by psoas muscle index (PMI) has been
shown to predict perioperative mortality and adverse events (AEs) after various surgical …

The 5-factor modified frailty index (mFI-5) is predictive of 30-day postoperative complications and readmission in patients with adult spinal deformity (ASD)

NV Shah, DJ Kim, N Patel, GA Beyer, DA Hollern… - Journal of Clinical …, 2022 - Elsevier
Background There is limited research regarding the association between the mFI-5 and
postoperative complications among adult spinal deformity (ASD) patients. Methods Using …

Frailty and sarcopenia: impact on outcomes following elective degenerative lumbar spine surgery

S Chotai, R Gupta, JS Pennings, AM Hymel, KR Archer… - Spine, 2022 - journals.lww.com
Study Design. This is a retrospective review of prospectively collected data. Objective. The
aim was to evaluate the impact of frailty and sarcopenia on outcomes after lumbar spine …

Evaluating frailty, mortality, and complications associated with metastatic spine tumor surgery using machine learning–derived body composition analysis

E Massaad, CP Bridge, A Kiapour… - … of Neurosurgery: Spine, 2022 - thejns.org
OBJECTIVE Cancer patients with spinal metastases may undergo surgery without clear
assessments of prognosis, thereby impacting the optimal palliative strategy. Because the …

Paraspinal sarcopenia is associated with worse patient-reported outcomes following laminoplasty for degenerative cervical myelopathy

ZW Pinter, R Reed, SE Townsley, AL Mikula… - Spine, 2023 - journals.lww.com
Study Design. Retrospective cohort study. Objective. The present study is the first to assess
the impact of paraspinal sarcopenia on patient-reported outcome measures (PROMs) …

Systemic considerations for the surgical treatment of spinal metastatic disease: a scoping literature review

MA MacLean, CJ Touchette, M Georgiopoulos… - The Lancet …, 2022 - thelancet.com
Systemic assessment is a pillar in the neurological, oncological, mechanical, and systemic
(NOMS) decision-making framework for the treatment of patients with spinal metastatic …

In-hospital mortality for the elderly with acute traumatic spinal cord injury

T Inglis, D Banaszek, CS Rivers, D Kurban… - Journal of …, 2020 - liebertpub.com
As the incidence of traumatic spinal cord injury (tSCI) in the elderly rises, clinicians are
increasingly faced with difficult discussions regarding aggressiveness of management …