Closed-loop vagus nerve stimulation for the treatment of cardiovascular diseases: state of the art and future directions
The autonomic nervous system exerts a fine beat-to-beat regulation of cardiovascular
functions and is consequently involved in the onset and progression of many cardiovascular …
functions and is consequently involved in the onset and progression of many cardiovascular …
The vagus nerve in cardiovascular physiology and pathophysiology: from evolutionary insights to clinical medicine
PS Rajendran, J Hadaya, SS Khalsa, C Yu… - Seminars in Cell & …, 2024 - Elsevier
The parasympathetic nervous system via the vagus nerve exerts profound influence over the
heart. Together with the sympathetic nervous system, the parasympathetic nervous system is …
heart. Together with the sympathetic nervous system, the parasympathetic nervous system is …
Outcomes of hypothalamic oxytocin neuron-driven cardioprotection after acute myocardial infarction
KJ Schunke, J Rodriguez, J Dyavanapalli… - Basic research in …, 2023 - Springer
Altered autonomic balance is a hallmark of numerous cardiovascular diseases, including
myocardial infarction (MI). Although device-based vagal stimulation is cardioprotective …
myocardial infarction (MI). Although device-based vagal stimulation is cardioprotective …
The plasticity of cardiac sympathetic nerves and its clinical implication in cardiovascular disease
H Kanazawa, K Fukuda - Frontiers in Synaptic Neuroscience, 2022 - frontiersin.org
The heart is electrically and mechanically controlled by the autonomic nervous system,
which consists of both the sympathetic and parasympathetic systems. It has been …
which consists of both the sympathetic and parasympathetic systems. It has been …
Noninvasive low-level tragus stimulation attenuates inflammation and oxidative stress in acute heart failure
Purpose Acute decompensated heart failure (ADHF) is associated with inflammation,
oxidative stress, and excess sympathetic drive. It is unknown whether neuromodulation …
oxidative stress, and excess sympathetic drive. It is unknown whether neuromodulation …
Transcutaneous vagus nerve stimulation ameliorates cardiac abnormalities in chronically stressed rats
V Agarwal, AS Kaushik, R Chaudhary… - Naunyn-Schmiedeberg's …, 2024 - Springer
Chronically stressed patients often have low vagal tone and increased levels of
proinflammatory cytokines, which increase their risk for developing cardiac dysfunction …
proinflammatory cytokines, which increase their risk for developing cardiac dysfunction …
Quantification of large transmural biopsies reveals heterogeneity in innervation patterns in chronic myocardial infarction
HS Chen, LM Voortman, JC van Munsteren… - Clinical …, 2023 - jacc.org
Background Abnormal cardiac innervation plays an important role in arrhythmogenicity after
myocardial infarction (MI). Data regarding reperfusion models and innervation abnormalities …
myocardial infarction (MI). Data regarding reperfusion models and innervation abnormalities …
Cardiac sympathetic hyperinnervation after myocardial infarction: a systematic review and qualitative analysis
HS Chen, L van Roon, J Schoones… - Annals of …, 2023 - Taylor & Francis
Background Cardiac sympathetic hyperinnervation after myocardial infarction (MI) is
associated with arrhythmogenesis and sudden cardiac death. The characteristics of cardiac …
associated with arrhythmogenesis and sudden cardiac death. The characteristics of cardiac …
Threshold adjusted vagus nerve stimulation after asphyxial cardiac arrest results in neuroprotection and improved survival
Background Vagus nerve stimulation (VNS) has shown therapeutic potential in a variety of
different diseases with many ongoing clinical trials. The role of VNS in reducing ischemic …
different diseases with many ongoing clinical trials. The role of VNS in reducing ischemic …
[HTML][HTML] Ultrasound-driven piezoelectret-based nanogenerator stimulates vagus nerve for myocardial infarction treatment
L Wang, X Li, Q Jin, R Wang, W Wang, X Cheng, C Tan… - Nano Energy, 2024 - Elsevier
Myocardial infarction (MI) stands as the predominant cause of morbidity and mortality within
the spectrum of cardiovascular diseases, with an unfavorable long-term prognosis. Vagus …
the spectrum of cardiovascular diseases, with an unfavorable long-term prognosis. Vagus …