Prevention and treatment of monkeypox

JG Rizk, G Lippi, BM Henry, DN Forthal, Y Rizk - Drugs, 2022 - Springer
Human monkeypox is a zoonotic orthopoxvirus with presentation similar to smallpox.
Monkeypox is transmitted incidentally to humans when they encounter infected animals …

[HTML][HTML] Monkeypox: epidemiology, pathogenesis, treatment and prevention

Y Huang, L Mu, W Wang - Signal Transduction and Targeted Therapy, 2022 - nature.com
Monkeypox is a zoonotic disease that was once endemic in west and central Africa caused
by monkeypox virus. However, cases recently have been confirmed in many nonendemic …

Monkeypox: a comprehensive review

H Harapan, Y Ophinni, D Megawati, A Frediansyah… - Viruses, 2022 - mdpi.com
The 2022 multi-country monkeypox outbreak in humans has brought new public health
adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The …

Monkeypox virus infections in humans

S Elsayed, L Bondy, WP Hanage - Clinical microbiology reviews, 2022 - Am Soc Microbiol
Human monkeypox is a viral zoonosis endemic to West and Central Africa that has recently
generated increased interest and concern on a global scale as an emerging infectious …

Pharmacokinetics and efficacy of a potential smallpox therapeutic, brincidofovir, in a lethal monkeypox virus animal model

CL Hutson, AV Kondas, MR Mauldin, JB Doty… - MSphere, 2021 - Am Soc Microbiol
Smallpox, caused by Variola virus (VARV), was eradicated in 1980; however, VARV
bioterrorist threats still exist, necessitating readily available therapeutics. Current …

Distinct monkeypox virus lineages co-circulating in humans before 2022

N Ndodo, J Ashcroft, K Lewandowski… - Nature medicine, 2023 - nature.com
The 2022 global mpox outbreak raises questions about how this zoonotic disease
established effective human-to-human transmission and its potential for further adaptation …

Disease history, pathogenesis, diagnostics, and therapeutics for human monkeypox disease: a comprehensive review

ARA Saied, M Dhawan, AA Metwally, ML Fahrni… - Vaccines, 2022 - mdpi.com
The monkeypox disease is a zoonotic-infectious disease that transmits between animals
and humans. It is caused by a double-stranded DNA virus belonging to the Orthopoxvirus …

A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19

S Jockusch, C Tao, X Li, TK Anderson, M Chien… - Antiviral research, 2020 - Elsevier
Abstract SARS-CoV-2, a member of the coronavirus family, is responsible for the current
COVID-19 worldwide pandemic. We previously demonstrated that five nucleotide analogues …

Preparing for the next viral threat with broad-spectrum antivirals

M Karim, CW Lo, S Einav - The Journal of Clinical …, 2023 - Am Soc Clin Investig
There is a large global unmet need for the development of countermeasures to combat
hundreds of viruses known to cause human disease and for the establishment of a …

Antiviral drugs for viruses other than human immunodeficiency virus

RR Razonable - Mayo Clinic Proceedings, 2011 - Elsevier
Most viral diseases, with the exception of those caused by human immunodeficiency virus,
are self-limited illnesses that do not require specific antiviral therapy. The currently available …