Valproic acid and progestin inhibit lesion growth and reduce hyperalgesia in experimentally induced endometriosis in rats
M Liu, X Liu, Y Zhang, SW Guo - Reproductive Sciences, 2012 - Springer
Accumulating evidence suggests that endometriosis is an epigenetic disease. This study
was designed to evaluate the effect of valproic acid (VPA) and progesterone (P4) in a rat …
was designed to evaluate the effect of valproic acid (VPA) and progesterone (P4) in a rat …
Effect of tumor necrosis factor-α on estrogen metabolism and endometrial cells: potential physiological and pathological relevance
SA Salama, MW Kamel, CR Diaz-Arrastia… - The Journal of …, 2009 - academic.oup.com
Context: Estrogen and its metabolites play a critical role in the pathophysiology of the
endometrium. The bioavailability of estrogen and estrogen metabolites in endometrial …
endometrium. The bioavailability of estrogen and estrogen metabolites in endometrial …
Liver receptor homolog-1 regulates the transcription of steroidogenic enzymes and induces the differentiation of mesenchymal stem cells into steroidogenic cells
T Yazawa, Y Inanoka, T Mizutani, M Kuribayashi… - …, 2009 - academic.oup.com
Steroidogenic factor-1 (SF-1, also known as Ad4BP) has been demonstrated to be a primary
transcriptional regulator of steroidogenic-related genes. However, mRNA for liver receptor …
transcriptional regulator of steroidogenic-related genes. However, mRNA for liver receptor …
Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis
J Ping, J Wang, L Liu, Y Yan, F Liu, Y Lei, H Wang - Toxicology, 2014 - Elsevier
Prenatal caffeine ingestion is one of the risk factors for intrauterine growth retardation
(IUGR). Adrenal plays a pivotal role, mainly through steroidogenesis, in the regulation of …
(IUGR). Adrenal plays a pivotal role, mainly through steroidogenesis, in the regulation of …
DNA methylation of HOXA10 in eutopic and ectopic endometrium
KL Andersson, C Bussani, M Fambrini… - Human …, 2014 - academic.oup.com
STUDY QUESTION Does the methylation status of the promoter region of the HOXA10 gene
differ in eutopic and ectopic endometrium? SUMMARY ANSWER The eutopic endometrium …
differ in eutopic and ectopic endometrium? SUMMARY ANSWER The eutopic endometrium …
MicroRNA23a and microRNA23b deregulation derepresses SF-1 and upregulates estrogen signaling in ovarian endometriosis
L Shen, S Yang, W Huang, W Xu… - The Journal of …, 2013 - academic.oup.com
Context: Steroidogenic factor (SF)-1 and its downstream target genes involved in estrogen
signaling are aberrantly expressed in ovarian endometriosis. Objective: Our objective was to …
signaling are aberrantly expressed in ovarian endometriosis. Objective: Our objective was to …
[HTML][HTML] Deoxyribonucleic acid methyltransferases and methyl-CpG-binding domain proteins in human endometrium and endometriosis
KJAF van Kaam, B Delvoux, A Romano, T D'Hooghe… - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To determine [1] expression levels of both DNA methyltransferases (DNMTs)
and methyl-CpG-binding domain proteins (MBDs) in human endometrium throughout the …
and methyl-CpG-binding domain proteins (MBDs) in human endometrium throughout the …
Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function
Endometriosis is a leading cause of pain and infertility affecting millions of women globally.
Herein, we characterize variation in DNA methylation (DNAm) and its association with …
Herein, we characterize variation in DNA methylation (DNAm) and its association with …
DNA methylation patterns of steroid receptor genes ESR1, ESR2 and PGR in deep endometriosis compromising the rectum
JL Meyer, D Zimbardi, S Podgaec… - International …, 2014 - spandidos-publications.com
Endometriosis is characterized by the presence of endometrial-like tissue located outside
the uterine cavity. Recent evidence suggests that endometriosis may be an epigenetic …
the uterine cavity. Recent evidence suggests that endometriosis may be an epigenetic …
[PDF][PDF] Epigenetic aberration of gene expression in endometriosis
M Izawa, F Taniguchi, N Terakawa… - Front Biosci (Elite …, 2013 - article.imrpress.com
Introduction 3. Estrogen and endometriosis 3.1. Pathophysiologic background of a high
estrogen environment in endometriosis 3.2. Aberrant aromatase expression in …
estrogen environment in endometriosis 3.2. Aberrant aromatase expression in …