Fir (e) ing the rhythm: inflammatory cytokines and cardiac arrhythmias
Inflammatory activation is increasingly recognized as a nonconventional risk factor for
arrhythmias, and experimental studies provided robust evidence that this association is …
arrhythmias, and experimental studies provided robust evidence that this association is …
Colchicine for COVID-19: targeting NLRP3 inflammasome to blunt hyperinflammation
A Bonaventura, A Vecchié, L Dagna, F Tangianu… - Inflammation …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is capable of inducing the
activation of NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) …
activation of NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) …
The role of IL-1 family of cytokines and receptors in pathogenesis of COVID-19
S Makaremi, A Asgarzadeh, H Kianfar… - Inflammation …, 2022 - Springer
A global pandemic has erupted as a result of the new brand coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …
respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic has been consociated …
[HTML][HTML] Cardiovascular protection by SGLT2 inhibitors–Do anti-inflammatory mechanisms play a role?
A Elrakaybi, K Laubner, Q Zhou, MJ Hug, J Seufert - Molecular metabolism, 2022 - Elsevier
Background Metabolic syndrome and related metabolic disturbances represent a state of
low-grade inflammation, which accelerates insulin resistance, type 2 diabetes (T2D) and …
low-grade inflammation, which accelerates insulin resistance, type 2 diabetes (T2D) and …
Interleukin-1 blockade with anakinra and heart failure following ST-segment elevation myocardial infarction: results from a pooled analysis of the VCUART clinical …
Aims ST-segment elevation myocardial infarction (STEMI) is associated with an intense
acute inflammatory response and an increased risk of death and heart failure (HF). In this …
acute inflammatory response and an increased risk of death and heart failure (HF). In this …
Programmed cell death: the pathways to severe COVID-19?
Two years after the emergence of SARS-CoV-2, our understanding of COVID-19 disease
pathogenesis is still incomplete. Despite unprecedented global collaborative scientific efforts …
pathogenesis is still incomplete. Despite unprecedented global collaborative scientific efforts …
The role of pro-Inflammatory cytokines in the pathogenesis of cardiovascular disease
H Zhang, NS Dhalla - International Journal of Molecular Sciences, 2024 - mdpi.com
With cardiovascular disease (CVD) being a primary source of global morbidity and mortality,
it is crucial that we understand the molecular pathophysiological mechanisms at play …
it is crucial that we understand the molecular pathophysiological mechanisms at play …
Interleukin-1α is a central regulator of leukocyte-endothelial adhesion in myocardial infarction and in chronic kidney disease
SJ Schunk, S Triem, D Schmit, S Zewinger, T Sarakpi… - Circulation, 2021 - Am Heart Assoc
Background: Cardiovascular diseases and chronic kidney disease (CKD) are highly
prevalent, aggravate each other, and account for substantial mortality. Both conditions are …
prevalent, aggravate each other, and account for substantial mortality. Both conditions are …
Blockage of interleukin-1β with canakinumab in patients with Covid-19
L Landi, C Ravaglia, E Russo, P Cataleta, M Fusari… - Scientific reports, 2020 - nature.com
There is the urgent need to study the effects of immunomodulating agents as therapy for
Covid-19. An observational, cohort, prospective study with 30 days of observation was …
Covid-19. An observational, cohort, prospective study with 30 days of observation was …
Dapagliflozin attenuates pressure overload-induced myocardial remodeling in mice via activating SIRT1 and inhibiting endoplasmic reticulum stress
F Ren, Z Xie, Y Jiang, X Guan, Q Chen… - Acta Pharmacologica …, 2022 - nature.com
Endoplasmic reticulum stress-mediated apoptosis plays a vital role in the occurrence and
development of heart failure. Dapagliflozin (DAPA), a new type of sodium-glucose …
development of heart failure. Dapagliflozin (DAPA), a new type of sodium-glucose …