Background Treatment-resistant depression (TRD) is considered a common clinical
condition often associated with relevant suicidal ideation and characterized by a severe …

Patients with treatment-resistant depression (TRD) have higher rates of relapse and
pronounced decreases in daily functioning and health-related quality of life compared to …

Major depressive disorder (MDD) is a prevalent and heterogeneous disorder. Although
there are many treatment options for MDD, patients with treatment-resistant depression …

Approximately one-third of patients with major depressive disorder (MDD) have treatment-
resistant depression (TRD). The TRAL study will evaluate the prevalence and impact of TRD …

BackgroundA large proportion of patients with major depressive disorder (MDD) have
treatment-resistant depression (TRD). The TRAL study examines the impact of TRD on …

Major depression is one of the most common psychiatric disorders with a high rate of
treatment resistance where new treatment options are urgently warranted. One of these new …

Background Major depressive disorder (MDD), particularly treatment-resistant ones, is
associated with abnormal fronto-limbic glucose metabolism. 10-Hz repetitive transcranial …

This post hoc analysis assessed the benefit–risk profile of esketamine nasal spray+ oral
antidepressant (AD) induction and maintenance treatment in patients with treatment …

This study registered consecutive cases to elucidate the efficacy of rTMS treatment for
depression within the Japanese public health insurance system. Of the 102 patients with …

Background The impact of treatment‐resistant depression (TRD) or prior suicidal
ideation/suicide attempt (SI/SA) on mortality by suicide among patients with major …