Objective Evaluate depression scores, response, and remission rates in patients with major
depression receiving adjunct therapy with folate (L-Methylfolate or folic acid) compared to …

Objectives To examine the strengths and limitations of existing data to provide guidance for
the use of folate supplements as treatment, with or without other psychotropic medications …

Given the moderate efficacy of the currently available antidepressants (ADs) in the treatment
of major depressive disorder (MDD), the identification of agents that are both able to …

Purpose This study aims, a systematic review and meta-analysis, to evaluate the effects of
folic acid (folate) on patients with depression. Design/methodology/approach Related …

Mood disorders affect more than 500 million people around the world. In the last decade,
their prevalence has increased, and many people suffer from nervousness, anxiety, and …

Background: International guideline recommendations for the use of folate and its
derivatives in the treatment of unipolar depressive disorders are confused and contradictory …

Objectives This is a meta-analysis of randomized controlled trials (RCTs) to examine the
efficacy and safety of adjunctive folate for three major mental disorders (schizophrenia …

Complementary and alternative medicine (CAM) encompasses a wide range of different non-
mainstream therapies that have been increasingly used for treatment or adjunctive treatment …

Background: Depression is a global burden with complex etiopathogenesis. Some nutrients
including vitamin D, B12, and folate deficiency have been considered risk factors for …

Objective Depression represents one of the most severe psychiatric disorders, characterized
by low mood episodes, as well as loss of interest. Major Depressive Episodes (MDE) …