Adipose tissue spexin in physical exercise and age-associated diseases
P Fang, R Ge, Y She, J Zhao, J Yan, X Yu, Y Jin… - Ageing Research …, 2022 - Elsevier
It is known that a strong association exists between a suboptimal lifestyle (physical inactivity
and sedentary behavior and/or high calorie diet) and increased propensity of developing …
and sedentary behavior and/or high calorie diet) and increased propensity of developing …
Emerging central and peripheral actions of spexin in feeding behavior, leptin resistance and obesity
M Yu, M Ju, P Fang, Z Zhang - Biochemical Pharmacology, 2022 - Elsevier
Consumption of a high calorie diet with irregular eating and sedentary behavior habits is
typical of the current suboptimal lifestyle, contributing to the development of metabolic …
typical of the current suboptimal lifestyle, contributing to the development of metabolic …
Spexin alleviates hypertension, hyperuricaemia, dyslipidemia and insulin resistance in high fructose diet induced metabolic syndrome in rats via enhancing PPAR-ɣ …
Spexin is a novel peptide implicated in obesity and energy homeostasis. The objective of the
current study was to evaluate the effect of spexin on blood pressure, insulin resistance, and …
current study was to evaluate the effect of spexin on blood pressure, insulin resistance, and …
[HTML][HTML] Identification of neurohypophysial hormones and the role of VT in the parturition of pregnant seahorses (Hippocampus erectus)
H Zhang, Y Liu, G Qin, Q Lin - Frontiers in Endocrinology, 2022 - frontiersin.org
Neurohypophysial hormones regulate the reproductive behavior of teleosts; however, their
role in the gestation and parturition of ovoviviparous fishes with male pregnancy …
role in the gestation and parturition of ovoviviparous fishes with male pregnancy …
Primary cilia, A‐kinase anchoring proteins and constitutive activity at the orphan G protein‐coupled receptor GPR161: A tale about a tail
K Patel, NJ Smith - British Journal of Pharmacology, 2024 - Wiley Online Library
Primary cilia are non‐motile antennae‐like structures responsible for sensing environmental
changes in most mammalian cells. Ciliary signalling is largely mediated by the Sonic …
changes in most mammalian cells. Ciliary signalling is largely mediated by the Sonic …
Normalization of spexin levels in patients with obesity submitted to bariatric surgery
A Bufano, G Iraci Sareri, C Ciuoli, S Cantara… - Obesity Surgery, 2024 - Springer
Purpose Spexin is expressed by white fat tissue and other endocrine organs. A negative
correlation between spexin and gluco-lipidic metabolism, energy homeostasis, and food …
correlation between spexin and gluco-lipidic metabolism, energy homeostasis, and food …
Exercise and metabolic health: the emerging roles of novel exerkines
Physical inactivity is a major cause of chronic diseases. It shortens the health span by
lowering the age of the first chronic disease onset, which leads to decreased quality of life …
lowering the age of the first chronic disease onset, which leads to decreased quality of life …
[HTML][HTML] Serum spexin differed in newly diagnosed type 2 diabetes patients according to body mass index and increased with the improvement of metabolic status
L Gu, S Yan, Y Huang, J Yang, Y Peng… - Frontiers in …, 2022 - frontiersin.org
Objective The aim of this study was to explore serum spexin levels in newly diagnosed type
2 diabetes mellitus (T2DM) patients with different body mass indexes (BMIs) and to …
2 diabetes mellitus (T2DM) patients with different body mass indexes (BMIs) and to …
Spexin-based galanin receptor 2 agonist improves renal injury in mice with type 2 diabetes
JJ Cha, BY Park, SG Yoon, HJ Park, JA Yoo… - Animal Cells and …, 2023 - Taylor & Francis
The spexin-based GALR2 agonist (NS200) is a novel drug, which has shown antidepressant
and anxiolytic action in a recent experimental study. In this study, we investigated the effects …
and anxiolytic action in a recent experimental study. In this study, we investigated the effects …
[HTML][HTML] New evidence for SPX2 in regulating the brain-pituitary reproductive axis of half-smooth tongue sole (Cynoglossus semilaevis)
B Wang, K Wang, Z Tian, A Cui, X Liu, Z Jin… - Frontiers in …, 2022 - frontiersin.org
Spexin (SPX) is an evolutionarily conserved neuropeptide, which was first identified in
human proteome by data mining. Two orthologs (SPX1 and SPX2) are present in some non …
human proteome by data mining. Two orthologs (SPX1 and SPX2) are present in some non …