Chronic constipation is a common, persistent condition affecting many patients worldwide,
presenting significant economic burden and resulting in substantial healthcare utilization. In …

Irritable bowel syndrome (IBS) is associated with diverse pathophysiologic mechanisms.
These mechanisms include increased abnormal colonic motility or transit, intestinal or …

Dietary fibers/probiotics may relieve constipation via optimizing gut microbiome, yet with
limited trial-based evidences. We aimed to evaluate the effects of formulas with dietary fibers …

Psyllium is a widely used treatment for constipation. It traps water in the intestine increasing
stool water, easing defaecation and altering the colonic environment. We aimed to assess …

METHODS: We searched PubMed and Embase for randomized controlled trials of≥ 4-week
duration that evaluated OTC preparations between 2004 and 2020. Studies were scored …

Chronic constipation is one of the most common digestive diseases encountered in clinical
practice. Constipation manifests as a variety of symptoms, such as infrequent bowel …

Background Chronic constipation is a common, heterogeneous disorder with multiple
symptoms and pathophysiological mechanisms. Patients are often referred to a …

Background & Aims Functional constipation is the most common of the disorders of gut-brain
interaction, affecting approximately 12% of the world population. Although classically …

Constipation in pregnancy Prevalence. Constipation is the second most commonly reported
GI symptom in pregnancy (2). Earlier studies indicated that 11%–38% of pregnant people …

Dietary fiber intake is one of the most influential and efficacious strategies for modulating the
gut microbiota. Said fiber can be digested by the microbiota itself, producing numerous …