By late 18 th or early 19 th century, albino rats became the most commonly used
experimental animals in numerous biomedical researches, as they have been recognized …

INTRODUCTION: Cardiovascular disease, the leading cause of death in much of the
modern world, is the common symptomatic end stage of a number of distinct diseases and …

Sterically stabilized liposomes are considered promising carriers of therapeutic agents
because they can facilitate controlled release of the drugs, thereby reducing drug-related …

Ten rats were subjected to total sleep deprivation (TSD) by the disk apparatus. All TSD rats
died or were sacrificed when death seemed imminent within 11-32 days. No anatomical …

Rats have long been recognized as a valuable biomedical research model, notably in the
investigation of aging, toxicology, addiction, and common human diseases such as diabetes …

Oxidative DNA damage is important in aging and the degenerative diseases of aging such
as cancer. Estimates commonly rely on measurements of 8-oxo-2′-deoxyguanosine …

The suitability of gadolinium complexes as magnetic resonance imaging contrast agents
depends on a number of factors. A thermodynamic relationship to toxicity exists if one …

MATERIALSAND METHODS Radiopharmaceuticals: 111ln-Labeled IgG Human
polyclonalIgG (Gammimune, Cutter Laborato lies, Emeryville, CA) was radiolabeled with †…

Glyphosate is the active ingredient and polyoxyethyleneamine is the surfactant present in
the herbicide Roundup® formulation commercialized in Brazil. The aim of this study was to …

The purpose of the present study was to examine myocardial antioxidant and oxidative
stress changes in male and female rats in the presence of physiological sex hormone …