Ibero-American Consensus Review and Incorporation of New Biomarkers for Clinical Practice in Colorectal Cancer

CE Bonilla, P Montenegro, JM O'Connor… - Cancers, 2023 - mdpi.com
Simple Summary The management of colorectal cancer has improved significantly due to
advances in molecular techniques. Thanks to these techniques, it has been possible to …

[HTML][HTML] Autotaxin production in the human breast cancer tumor microenvironment mitigates tumor progression in early breast cancers

MGK Benesch, R Wu, X Tang, DN Brindley… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Autotaxin (ATX) is a secreted enzyme that produces extracellular lysophosphatidate in
physiological wound healing. ATX is overexpressed in many cancers to promote growth …

Resistance to cell death in mucinous colorectal cancer—A review

E O'Connell, IS Reynolds, DA McNamara, JP Burke… - Cancers, 2021 - mdpi.com
Simple Summary Mucinous colorectal cancer is characterised by abundant mucin
glycoprotein production and is associated with resistance to chemotherapy-based …

[HTML][HTML] Clinicopathological characteristics and outcomes of colorectal mucinous adenocarcinoma: a retrospective analysis from China

A Huang, Y Yang, Z Sun, H Hong, J Chen… - Frontiers in …, 2024 - frontiersin.org
Background Mucinous adenocarcinoma (MAC) is a unique subtype of colorectal cancer and
its prognostic value remains controversial. This study aimed to compare the …

[HTML][HTML] Epidemiologic characteristics and risk factors associated with overall survival for patients with mucinous colorectal cancer: A population-based study

J Jiang, XW Tang, S Huang, N Hu, Y Chen… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Mucinous adenocarcinoma (MC) has attracted much attention as a distinct
histologic subtype of colorectal cancer in recent years. However, data about its …

Location has prognostic impact on the outcome of colorectal mucinous adenocarcinomas

MGK Benesch, ED Nelson, SBL O'Brien - Cancers, 2023 - mdpi.com
Simple Summary Mucinous adenocarcinomas are an uncommon tumor type that arise
primarily in the large intestine, characterized by the overexpression of a jelly-like substance …

[HTML][HTML] Epidemiology of Adenosquamous Carcinomas

MGK Benesch, VO Ramos-Santillan… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Background Adenosquamous carcinomas (ASCs) are a very rare histology containing
cancer cells with both glandular-like (adeno) and squamous cell histologies, comprising …

Effects of tumor localization, age, and stage on the outcomes of gastric and colorectal signet ring cell adenocarcinomas

MGK Benesch, A Mathieson, SBL O'Brien - Cancers, 2023 - mdpi.com
Simple Summary Signet ring cell adenocarcinomas are an extremely rare type of cancer that
arise primarily in the stomach and colon. These cancers tend to present at an earlier age …

[HTML][HTML] High EIF4EBP1 expression reflects mTOR pathway activity and cancer cell proliferation and is a biomarker for poor breast cancer prognosis

ED Nelson, MGK Benesch, R Wu… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) is regulated by the
mTOR (mammalian target of rapamycin) signaling pathway. Phosphorylated EIF4EBP1 …

Does docetaxel matter in metastatic gastric cancer? FOLFOX versus FLOT regimens as first-line treatment

F Gürler, A İlhan, DC Güven, O Turhan, BK İnci… - Anti-cancer …, 2022 - journals.lww.com
We aimed to compare the efficacy and the safety of the FOLFOX and the FLOT regimens in
metastatic gastric cancer (mGC) as first-line treatment. It was a retrospective multicenter …