Functional states of myeloid cells in cancer
L van Vlerken-Ysla, YY Tyurina, VE Kagan… - Cancer cell, 2023 - cell.com
Myeloid cells, comprised of macrophages, dendritic cells, monocytes, and granulocytes,
represent a major component of the tumor microenvironment (TME) and are critically …
represent a major component of the tumor microenvironment (TME) and are critically …
Novel tumor-associated macrophage populations and subpopulations by single cell RNA sequencing
J Wang, N Zhu, X Su, Y Gao, R Yang - Frontiers in Immunology, 2024 - frontiersin.org
Tumor-associated macrophages (TAMs) are present in almost all solid tumor tissues.
16They play critical roles in immune regulation, tumor angiogenesis, tumor stem cell …
16They play critical roles in immune regulation, tumor angiogenesis, tumor stem cell …
Fibronectin 1 as a key gene in the genesis and progression of cadmium-related bladder cancer
L Zhang, Y Wang, M Song, A Chang, W Zhuo… - Biological Trace Element …, 2023 - Springer
Exposure to cadmium (Cd), a non-essential heavy metal, leads to the malignant
transformation of urothelial cells and promotes bladder cancer (BC) development, but the …
transformation of urothelial cells and promotes bladder cancer (BC) development, but the …
[HTML][HTML] SERPINE1 as an independent prognostic marker and therapeutic target for nicotine-related oral carcinoma
X Guo, Z Sun, H Chen, J Ling, H Zhao… - Clinical and …, 2022 - synapse.koreamed.org
Objectives Nicotine is an ingredient of tobacco, and exposure to nicotine increases the risks
of various cancers, including oral cancer. Previous studies have focused on the addictive …
of various cancers, including oral cancer. Previous studies have focused on the addictive …
Single-cell transcriptome analysis profiling lymphatic invasion-related TME in colorectal cancer
L Wang, L Ma, Z Song, L Zhou, K Chen, X Wang… - Scientific Reports, 2024 - nature.com
Lymphatic invasion (LI) is extremely aggressive and induces worse prognosis among
patients with colorectal cancer (CRC). Thus, it is critical to characterize the cellular and …
patients with colorectal cancer (CRC). Thus, it is critical to characterize the cellular and …
SPP1+ macrophages in colorectal cancer: Markers of malignancy and promising therapeutic targets
Z Xie, G Zheng, L Niu, K Du, R Li, H Dan, L Duan… - Genes & …, 2024 - Elsevier
SPP1+ macrophages have been identified as key players in the colorectal cancer (CRC)
tumor microenvironment, but their function remains unclear. This study integrated single-cell …
tumor microenvironment, but their function remains unclear. This study integrated single-cell …
Identification of immune-related genes in the prognosis of head and neck cancer using a novel prognostic signature model
A Chang, Y Wang, X Guo, Z Sun, J Ling, J Pan… - Oral Surgery, Oral …, 2023 - Elsevier
Background Increasing evidence indicates that the immune response plays a critical role in
the development of head and neck cancer (HNC). We aimed to develop an immune-related …
the development of head and neck cancer (HNC). We aimed to develop an immune-related …
MYO1B as a prognostic biomarker and a therapeutic target in Arecoline‐associated oral carcinoma
Z Sun, X Guo, H Chen, J Ling, H Zhao… - Molecular …, 2023 - Wiley Online Library
Background Arecoline, the main component of betel nut, induces malignant transformation
of oral cells through complicated unclear mechanisms. Thus, we aimed to screen the key …
of oral cells through complicated unclear mechanisms. Thus, we aimed to screen the key …
Risk prediction for dermatomyositis-associated hepatocellular carcinoma
X Zhang, Y Ma, K Liu, L Chen, L Ding, W Ma, B Chen - BMC bioinformatics, 2023 - Springer
Objective To explore dermatomyositis signature genes as potential biomarkers of
hepatocellular carcinoma and their associated molecular regulatory mechanisms. Methods …
hepatocellular carcinoma and their associated molecular regulatory mechanisms. Methods …
SPP1+ macrophages: A malignant macrophage subset in the colorectal cancer microenvironment revealed by single-cell sequencing
J Zheng, Z Xie, L Niu, G Zheng, R Li, H Dan, L Duan… - 2022 - researchsquare.com
Accumulating single-cell studies suggest that SPP1+ macrophages are key players in the
tumor microenvironment. However, a systematic investigation of SPP1+ macrophages in …
tumor microenvironment. However, a systematic investigation of SPP1+ macrophages in …