Despite the well-known sex dimorphism in cardiovascular disease traits, the exact genetic,
molecular, and cellular underpinnings of these differences are not well understood. A …

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable cardiomyopathy
characterized by a predominantly arrhythmic presentation. It represents the leading cause of …

Clinical studies suggest low testosterone levels are associated with cardiac arrhythmias,
especially in later life. We investigated whether chronic exposure to low circulating …

Abstract Context The T4DM study randomized 1007 men with impaired glucose tolerance or
newly diagnosed diabetes to testosterone undecanoate (TU, 1000 mg) or matching placebo …

Nav1. 5 is the predominant cardiac sodium channel subtype, encoded by the SCN5A gene,
which is involved in the initiation and conduction of action potentials throughout the heart …

Arrhythmogenic cardiomyopathy (ACM) is a hereditary myocardial disease characterized by
the replacement of the ventricular myocardium with fibrous fatty deposits. ACM is usually …

Context Sex hormones have been identified as cardiovascular risk factors, whereas the
relationship between sex hormones and the risk of arrhythmias in men has not yet been well …

Background: Patients with chronic kidney disease (CKD) are at increased risk of developing
cardiac arrhythmogenesis and sudden cardiac death; however, the basis for this association …

Objective To study the relationship between the sex probability derived from the artificial
intelligence (AI)-augmented electrocardiogram (ECG) and sex hormone levels. Patients and …

Voltage-gated calcium channels (VGCCs) and estrogen receptors are important cellular
proteins that have been shown to interact with each other across varied cells and tissues …