Targeted therapy for non-small-cell lung cancer: past, present and future

PM Forde, DS Ettinger - Expert review of anticancer therapy, 2013 - Taylor & Francis
Therapy for advanced non-small-cell lung cancer has developed significantly with new
awareness of histologic subtype as an important factor in guiding treatment and the …

The possibility of traditional chinese medicine as maintenance therapy for advanced nonsmall cell lung cancer

W Xu, G Yang, Y Xu, Q Zhang, Q Fu… - Evidence‐Based …, 2014 - Wiley Online Library
Lung cancer has become the leading cause of cancer deaths, with nonsmall cell lung
cancer (NSCLC) accounting for around 80% of lung cancer cases. Chemotherapy is the …

A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non–small cell lung cancer …

S Alfonso, A Valdés-Zayas, ER Santiesteban… - Clinical Cancer …, 2014 - AACR
Purpose: Racotumomab-alum is an anti-idiotype vaccine targeting the NeuGcGM3 tumor-
associated ganglioside. This clinical trial was conducted to provide a preliminary estimate of …

[HTML][HTML] Survival of NSCLC patients treated with cimavax-EGF as switch maintenance in the real-world scenario

YIF Vega, DLP González, SCA Sarmiento… - Journal of …, 2023 - ncbi.nlm.nih.gov
Abstract Introduction: In Cuba, lung cancer represents the first cause of mortality for both
sexes. Non-small cell lung cancer (NSCLC) is the most prevalent histology. Overall, 75-85 …

[HTML][HTML] Maintenance chemotherapy with Chinese herb medicine formulas vs. with placebo in patients with advanced non-small cell lung cancer after first-line …

Q Wang, L Jiao, S Wang, P Chen, L Bi… - Frontiers in …, 2018 - frontiersin.org
Background: Chinese Herb Medicine Formulas (CHMF) was reported to improve the quality
of life (QoL) in advanced NSCLC patients. The present study was designed to investigate …

The evolving role of pemetrexed disodium for the treatment of non-small cell lung cancer

G Rossi, A Alama, C Genova, E Rijavec… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Non-small cell lung cancer (NSCLC) remains one of the big cancer killers,
despite the introduction of a number of approved therapeutics in recent times. Pemetrexed is …

Cost-effectiveness analysis of the addition of bevacizumab to chemotherapy as induction and maintenance therapy for metastatic non-squamous non-small-cell lung …

H Zheng, L Xie, M Zhan, F Wen, T Xu, Q Li - Clinical and Translational …, 2018 - Springer
Background The BEYOND trial found that the addition of bevacizumab (B) to paclitaxel–
carboplatin (PC) chemotherapy provided a significant clinical benefit to Chinese patients …

Pemetrexed for the treatment of non-small cell lung cancer

C Genova, E Rijavec, A Truini, S Coco… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Non-small cell lung cancer (NSCLC) is a major cause of cancer-related death
worldwide. Although advanced NSCLC is still incurable, various anti-neoplastic agents have …

Design issues in randomized clinical trials of maintenance therapies

B Freidlin, RF Little, EL Korn - Journal of the National Cancer …, 2015 - academic.oup.com
A potential therapeutic strategy for patients who respond (or have stable disease) on a fixed-
duration induction therapy is to receive maintenance therapy, typically given for a prolonged …

[HTML][HTML] Bayesian network meta-comparison of maintenance treatments for stage IIIb/IV non-small-cell lung cancer (NSCLC) patients with good performance status not …

P San Tan, G Lopes, S Acharyya, M Bilger… - European Journal of …, 2015 - Elsevier
Background Recent trials have suggested that maintenance treatments improve outcomes
for patients not progressing after first-line therapy for advanced non-small-cell lung cancer …