Molecular epidemiology investigations are notoriously challenging in the leprosy field
mainly because the inherent characteristics of the disease as well as its yet uncultivated …

Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae, the
annual new case detection in 2019 was 202,189 globally. Measuring endemicity levels and …

Background Leprosy has been treated with multidrug therapy, which has been distributed for
free across the globe and regarded as highly efficient. However, the impossibility of growing …

Mycobacterium leprae, the causative agent of leprosy, is an unculturable bacterium with a
considerably reduced genome (3.27 Mb) compared to homologues mycobacteria from the …

Mycobacterium leprae is classified into four SNP genotypes and 16 subtypes (from 1A to 4P)
that exhibit phylogeographical association reported from around the world. Among them …

Background: Brazil has the second largest number of leprosy cases worldwide, and the state
of São Paulo has been considered non-endemic since 2006. Methods: We analyzed 16 …

Objectives The present study analyzed the impact of the COVID-19 pandemic on the
prevalence and incidence of new leprosy cases, as well as the diversity, distribution, and …

Mycobacterium leprae, the causative agent of leprosy, is an unculturable bacterium with a
considerably reduced genome (3.27 Mb) compared to homologues mycobacteria from the …

Infection with Mycobacterium leprae, the causative organism of leprosy, is still endemic in
numerous parts of the world including the southwestern United States. The broad variation …

Leprosy is a neglected tropical disease that leads to physical disability and social
discrimination. The active surveillance of new cases and vigilance for drug resistance can …