Bioactivity of dietary polyphenols: The role of metabolites

SV Luca, I Macovei, A Bujor, A Miron… - Critical reviews in …, 2020 - Taylor & Francis
A polyphenol-rich diet protects against chronic pathologies by modulating numerous
physiological processes, such as cellular redox potential, enzymatic activity, cell proliferation …

Flavonoid metabolism: The interaction of metabolites and gut microbiota

K Murota, Y Nakamura, M Uehara - Bioscience, biotechnology …, 2018 - academic.oup.com
Several dietary flavonoids exhibit anti-oxidative, anti-inflammatory, and anti-osteoporotic
activities relevant to prevention of chronic diseases, including lifestyle-related diseases …

1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses

Y Zou, W Xue, G Luo, Z Deng, P Qin, R Guo… - Nature …, 2019 - nature.com
Reference genomes are essential for metagenomic analyses and functional characterization
of the human gut microbiota. We present the Culturable Genome Reference (CGR), a …

An updated review of dietary isoflavones: Nutrition, processing, bioavailability and impacts on human health

K Zaheer, M Humayoun Akhtar - Critical reviews in food science …, 2017 - Taylor & Francis
Isoflavones (genistein, daidzein, and glycitein) are bioactive compounds with mildly
estrogenic properties and often referred to as phytoestrogen. These are present in …

[HTML][HTML] Estrogenic flavonoids and their molecular mechanisms of action

R Kiyama - The Journal of Nutritional Biochemistry, 2023 - Elsevier
Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

Metabolic fate of polyphenols in the human superorganism

J van Duynhoven, EE Vaughan… - Proceedings of the …, 2011 - National Acad Sciences
Dietary polyphenols are components of many foods such as tea, fruit, and vegetables and
are associated with several beneficial health effects although, so far, largely based on …

In vitro metabolism of anthocyanins by human gut microflora

AM Aura, P Martin-Lopez, KA O'Leary… - European journal of …, 2005 - Springer
Background Only a small part of the dietary anthocyanins are absorbed. Thus large amounts
of the ingested compounds are likely to enter the colon. In vitro and in vivo studies have …

Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota

CT Peterson, V Sharma, L Elmén… - Clinical & Experimental …, 2015 - academic.oup.com
The distal gut harbours∼ 1013 bacteria, representing the most densely populated
ecosystem known. The functional diversity expressed by these communities is enormous …

Microbial metabolism of dietary phenolic compounds in the colon

AM Aura - Phytochemistry Reviews, 2008 - Springer
Plant foods contain substantial amounts of phenolic compounds. Dietary interventions with
phenolic supplementation show that phenolic compounds are transformed into phenolic …

Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health

C Atkinson, CL Frankenfeld… - … biology and medicine, 2005 - journals.sagepub.com
The indigenous intestinal microflora are involved in a variety of processes within the human
body, and are important for maintaining host health. As such, interindividual differences in …