Drug discovery from natural sources
Organic compounds from terrestrial and marine organisms have extensive past and present
use in the treatment of many diseases and serve as compounds of interest both in their …
use in the treatment of many diseases and serve as compounds of interest both in their …
Can invalid bioactives undermine natural product-based drug discovery?
J Bisson, JB McAlpine, JB Friesen… - Journal of medicinal …, 2016 - ACS Publications
High-throughput biology has contributed a wealth of data on chemicals, including natural
products (NPs). Recently, attention was drawn to certain, predominantly synthetic …
products (NPs). Recently, attention was drawn to certain, predominantly synthetic …
Documentation of herbal medicines used for the treatment and management of human diseases by some communities in southern Ghana
AA Boadu, A Asase - Evidence‐Based Complementary and …, 2017 - Wiley Online Library
Traditional medicine is an important component of the health care system of most
developing countries. However, indigenous knowledge about herbal medicines of many …
developing countries. However, indigenous knowledge about herbal medicines of many …
Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo
ML Gou, K Men, HS Shi, ML Xiang, J Zhang, J Song… - Nanoscale, 2011 - pubs.rsc.org
Curcumin is an effective and safe anticancer agent, but its hydrophobicity inhibits its clinical
application. Nanotechnology provides an effective method to improve the water solubility of …
application. Nanotechnology provides an effective method to improve the water solubility of …
Antibacterial natural products in medicinal chemistry—exodus or revival?
F Von Nussbaum, M Brands, B Hinzen… - Angewandte Chemie …, 2006 - Wiley Online Library
To create a drug, nature's blueprints often have to be improved through semisynthesis or
total synthesis (chemical postevolution). Selected contributions from industrial and academic …
total synthesis (chemical postevolution). Selected contributions from industrial and academic …
New aspects of natural products in drug discovery
KS Lam - Trends in microbiology, 2007 - cell.com
During the past 15 years, most large pharmaceutical companies have decreased the
screening of natural products for drug discovery in favor of synthetic compound libraries …
screening of natural products for drug discovery in favor of synthetic compound libraries …
Plant-derived compounds in clinical trials
Plants remain an important source of new drugs, new drug leads and new chemical entities.
The plant-based drug discovery resulted mainly in the development of anticancer and anti …
The plant-based drug discovery resulted mainly in the development of anticancer and anti …
[图书][B] Chitin, chitosan, oligosaccharides and their derivatives: biological activities and applications
SK Kim - 2010 - books.google.com
Providing comprehensive coverage of the biological activities and industrial applications of
Chitin, Chitosan, oligosaccharides, and their derivatives, this book presents a balance of …
Chitin, Chitosan, oligosaccharides, and their derivatives, this book presents a balance of …
Synthesis, reactions and application of chalcones: A systematic review
Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …
[PDF][PDF] Natural sources as potential anti-cancer agents: A review
A Bhanot, R Sharma, MN Noolvi - International journal of phytomedicine, 2011 - core.ac.uk
Natural products remain an important source of new drugs, new drug leads and new
chemical entities. The plant based drug discovery resulted mainly in the development of …
chemical entities. The plant based drug discovery resulted mainly in the development of …