Cortical excitability and plasticity in Alzheimer's disease and mild cognitive impairment: a systematic review and meta-analysis of transcranial magnetic stimulation …
Background Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation
technique. When stimulation is applied over the primary motor cortex and coupled with …
technique. When stimulation is applied over the primary motor cortex and coupled with …
The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease
Y Tang, Y Yan, J Mao, J Ni, H Qing - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …
TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans
CS Latimer, JG Stair, JC Hincks… - Disease Models & …, 2022 - journals.biologists.com
Although amyloid β (Aβ) and tau aggregates define the neuropathology of Alzheimer's
disease (AD), TDP-43 has recently emerged as a co-morbid pathology in more than half of …
disease (AD), TDP-43 has recently emerged as a co-morbid pathology in more than half of …
Semantic processing and neurobiology in Alzheimer's disease and mild cognitive impairment
VN Almeida, M Radanovic - Neuropsychologia, 2022 - Elsevier
In the present theoretical review we will perform a critical surveillance of linguistic and
semantic processing in Mild Cognitive Impairment and Alzheimer's disease, explicitly …
semantic processing in Mild Cognitive Impairment and Alzheimer's disease, explicitly …
Mitochondrial SIRT3 deficiency results in neuronal network hyperexcitability, accelerates age-related Aβ pathology, and renders neurons vulnerable to Aβ Toxicity
Aging is the major risk factor for Alzheimer's disease (AD). Mitochondrial dysfunction and
neuronal network hyperexcitability are two age-related alterations implicated in AD …
neuronal network hyperexcitability are two age-related alterations implicated in AD …
Ketogenic-Mimicking Diet as a Therapeutic Modality for Bipolar Disorder: Biomechanistic Rationale and Protocol for a Pilot Clinical Trial
JLB Bohnen, TP Wigstrom, AM Griggs, S Roytman… - Nutrients, 2023 - mdpi.com
There is growing interest in the investigation of ketogenic diets as a potential therapy for
bipolar disorder. The overlapping pharmacotherapies utilized for both bipolar disorder and …
bipolar disorder. The overlapping pharmacotherapies utilized for both bipolar disorder and …
[HTML][HTML] Disrupted Balance of Gray Matter Volume and Directed Functional Connectivity in Mild Cognitive Impairment and Alzheimer's Disease
Y Xiong, C Ye, R Sun, Y Chen, X Zhong… - Current Alzheimer …, 2023 - ncbi.nlm.nih.gov
Background Alterations in functional connectivity have been demonstrated in Alzheimer's
disease (AD), an age-progressive neurodegenerative disorder that affects cognitive function; …
disease (AD), an age-progressive neurodegenerative disorder that affects cognitive function; …
Somatostatin and the pathophysiology of Alzheimer's disease
VN Almeida - Ageing Research Reviews, 2024 - Elsevier
Among the central features of Alzheimer's disease (AD) progression are altered levels of the
neuropeptide somatostatin (SST), and the colocalisation of SST-positive interneurons (SST …
neuropeptide somatostatin (SST), and the colocalisation of SST-positive interneurons (SST …
Parvalbumin Interneuron Dysfunction in Neurological Disorders: Focus on Epilepsy and Alzheimer's Disease
B Leitch - International Journal of Molecular Sciences, 2024 - mdpi.com
Parvalbumin expressing (PV+) GABAergic interneurons are fast spiking neurons that
provide powerful but relatively short-lived inhibition to principal excitatory cells in the brain …
provide powerful but relatively short-lived inhibition to principal excitatory cells in the brain …
Personalized, Precision Medicine to Cure Alzheimer's Dementia: Approach# 1
J Fessel - International Journal of Molecular Sciences, 2024 - mdpi.com
The goal of the treatment for Alzheimer's dementia (AD) is the cure of dementia. A literature
review revealed 18 major elements causing AD and 29 separate medications that address …
review revealed 18 major elements causing AD and 29 separate medications that address …