For hundreds of years, the drug discovery and development industry has aimed at
identifying single components with a clear mechanism of action as desirable candidates for …

A variety of phytocompounds contained in medical plants have been used as medication,
including Kampo (traditional Japanese) medicine. Phytochemicals are one category of the …

Ferroptosis is a form of regulated nonapoptotic cell death associated with iron-dependent
lipid peroxidation. Previous studies have shown that ferroptosis is involved in the occurrence …

Ethnopharmacological relevance Naringenin (NGN) is a widely distributed flavonoid with
potent antioxidant and neuroprotective properties. Neuroprotective agents play a crucial role …

Background Surgical resection combined with radiotherapy and chemotherapy remains a
common clinical treatment for glioblastoma multiforme (GBM). However, the therapeutic …

Background Acute lung injury (ALI) is a serious health issue which causes significant
morbidity and mortality. Inflammation is an important factor in the pathogenesis of ALI. Even …

Osteoarthritis (OA) is an age-related joint disease in which inflammation and extracellular
matrix (ECM) degradation play a crucial role in the destruction of articular cartilage …

Sepsis is a common but critical illness in patients admitted to the intensive care unit and is
associated with high mortality. Although there are many treatments for sepsis, specific and …

Abstract Ethnopharmacological relevance Shiwei Qingwen decoction (SWQ), a Chinese
herbal formula based on the classic traditional Chinese medicine prescription Yu Ping Feng …

Objective: Aloe-emodin (AE) is an anthraquinone compound extracted from the rhizome of
the natural plant rhubarb. Initially, it was shown that AE exerts an anti-inflammatory effect …