The propensity score is defined as the probability of each individual study subject being
assigned to a group of interest for comparison purposes. Propensity score adjustment is a …

Since their introduction in the 1980s, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitors (statins) have emerged as the one of the best-selling medication …

Background: Adjusting for large numbers of covariates ascertained from patients' health care
claims data may improve control of confounding, as these variables may collectively be …

Often the literature makes assertions of medical product effects on the basis of 'p< 0.05'. The
underlying premise is that at this threshold, there is only a 5% probability that the observed …

To reduce bias by residual confounding in nonrandomized database studies, the high-
dimensional propensity score (hd-PS) algorithm selects and adjusts for previously …

Objectives To investigate whether COVID-19 patients with pulmonary embolism had higher
mortality and assess the utility of d-dimer in predicting acute pulmonary embolism. Patients …

Background Many patients at high risk of cardiovascular disease do not achieve
recommended low-density lipoprotein cholesterol (LDL-C) goals. This study compared the …

The GALAXY Program is a series of clinical studies investigating the efficacy and tolerability
of rosuvastatin in line with the hypothesis that the statin with the greatest efficacy for …

Drug Class Review HMG-CoA Reductase Inhibitors (Statins) and Fixed-dose Combination
Products Containing a Statin Page 1 Drug Class Review HMG-CoA Reductase Inhibitors (Statins) …

Combinations of statins and fibrates may be increasingly prescribed to achieve lipid goals in
high-risk patients and those with other cardiovascular risk factors, such as mixed …