Novel inhibitor-based therapies for thyroid cancer—An update

M Ratajczak, D Gaweł, M Godlewska - International journal of molecular …, 2021 - mdpi.com
Thyroid cancers (TCs) are the most common tumors of the endocrine system and a constant
rise in the number of TC cases has been observed for the past few decades. TCs are one of …

Strategies for radioiodine treatment: what's new

C Sparano, S Moog, J Hadoux, C Dupuy, A Al Ghuzlan… - Cancers, 2022 - mdpi.com
Simple Summary Radioactive iodine treatment is the oldest targeted therapy for
differentiated thyroid cancer. It can be used for normal thyroid remnant ablation (in order to …

Comparison of the Therapeutic Effects of [211At]NaAt and [131I]NaI in an NIS-Expressing Thyroid Cancer Mouse Model

T Watabe, Y Liu, K Kaneda-Nakashima, T Sato… - International Journal of …, 2022 - mdpi.com
Astatine (211At) is an alpha-emitter with a better treatment efficacy against differentiated
thyroid cancer compared with iodine (131I), a conventional beta-emitter. However, its …

Radioactive iodine therapy does not improve cancer-specific survival in Hürthle cell carcinoma of the thyroid

X Wang, X Zheng, J Zhu, Z Li… - The Journal of Clinical …, 2022 - academic.oup.com
Context It is unclear whether radioactive iodine (RAI) therapy could improve cancer-specific
survival (CSS) in patients with Hürthle cell carcinoma (HCC) of the thyroid. Objective To …

Radioactive iodine in low-to intermediate-risk papillary thyroid cancer

H Zhao, Y Gong - Frontiers in Endocrinology, 2022 - frontiersin.org
It remains controversial whether papillary thyroid cancer (PTC) patients with low-to
intermediate-risk disease should receive radioactive iodine (RAI) after total thyroidectomy …

Radioactive iodine in differentiated thyroid carcinoma: a systematic AGREE II clinical practice guideline appraisal

S Monos, C Fritz, J Harris, D Romeo… - … –Head and Neck …, 2024 - Wiley Online Library
Objective Identify and appraise clinical practice guidelines (CPGs) for radioactive iodine
(RAI) indications in differentiated thyroid carcinoma (DTC), and the treatment for radioactive …

Bambus [4, 6] urils as dual scaffolds for multivalent iminosugar presentation and ion transport: access to unprecedented glycosidase-directed anion caging agents

M Lafosse, Y Liang, JP Schneider, E Cartier… - Molecules, 2022 - mdpi.com
Bambusurils, BU [4] and BU [6], were used for the first time as multivalent scaffolds to link
glycosidases inhibitors derived from 1-deoxynojirimycin (DNJ). Two linear DNJ ligands …

Lobectomy or total thyroidectomy-where is the pendulum now for differentiated thyroid cancer?

OJ Fackelmayer, WB Inabnet 3rd - Surgical Oncology Clinics of …, 2023 - europepmc.org
Thyroid surgery remains an essential treatment of thyroid cancer. The historical one-size-fits-
all approach to differentiated (papillary and follicular) thyroid carcinoma of total …

Effect to Therapy of Sodium-Iodine Symporter Expression by Alpha-Ray Therapeutic Agent via Sodium/Iodine Symporter

K Kaneda-Nakashima, Y Shirakami, T Watabe… - International Journal of …, 2022 - mdpi.com
This study confirmed the effect of sodium/iodine symporter (NIS) expression on existing
drugs by in vitro and in vivo tests using cultured cell lines. The tumor growth inhibitory effect …

Nuclear Imaging and Therapy of Thyroid Disorders

S Muzahir, EE Grady - Exon Publications, 2023 - exonpublications.com
This chapter reviews the basics of molecular imaging in thyroid disease and special
considerations in radioiodine therapy of benign diseases such as Graves' disease …