Inflammasomes are multi-protein signaling complexes that trigger the activation of
inflammatory caspases and the maturation of interleukin-1β. Among various inflammasome …

Reactive oxygen species (ROS), highly reactive molecules, are produced by living
organisms as a result ofnormal cellular metabolism and environmental factors, and can …

Background/Aims: Reperfusion after an ischaemic insult might cause infarct extension.
Mesenchymal stem cell (MSC)-derived exosomes could attenuate myocardial remodelling in …

Diabetes mellitus type 2 (T2DM) is a metabolic disorder develops due to the overproduction
of free radicals where oxidative stress could contribute it. Possible factors are defective …

Xanthine oxidoreductase (XOR) is the enzyme that catalyzes the oxidation of hypoxanthine
to xanthine and xanthine to uric acid and is widely distributed among species. In addition to …

The dietary requirement for an essential trace element is an intake level which meets a
specified criterion for adequacy and thereby minimizes risk of nutrient deficiency or excess …

Protein oxidative modifications, also known as protein oxidation, are a major class of protein
posttranslational modifications. They are caused by reactions between protein amino acid …

It is now well established that reactive oxygen species (ROS), reactive nitrogen species
(RNS), and a basal level of oxidative stress are essential for cell survival. It is also well …

Reactive oxygen species (ROS) can be both beneficial and deleterious. Under normal
physiological conditions, ROS production is tightly regulated, and ROS participate in both …

Two risk factors for the development and progression of cancers that are amenable to life
style modification are chronic inflammation and the metabolic syndrome. This review …