Polysubstance use in the US opioid crisis

WM Compton, RJ Valentino, RL DuPont - Molecular Psychiatry, 2021 - nature.com
Interventions to address the US opioid crisis primarily target opioid use, misuse, and
addiction, but because the opioid crisis includes multiple substances, the opioid specificity of …

Psychopathy

SA De Brito, AE Forth, AR Baskin-Sommers… - Nature Reviews …, 2021 - nature.com
Psychopathy is a personality disorder characterized by a constellation of affective,
interpersonal, lifestyle and antisocial features whose antecedents can be identified in a …

A large-scale genome-wide association study meta-analysis of cannabis use disorder

EC Johnson, D Demontis, TE Thorgeirsson… - The Lancet …, 2020 - thelancet.com
Background Variation in liability to cannabis use disorder has a strong genetic component
(estimated twin and family heritability about 50–70%) and is associated with negative …

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

The ENIGMA Toolbox: multiscale neural contextualization of multisite neuroimaging datasets

S Larivière, C Paquola, B Park, J Royer, Y Wang… - Nature …, 2021 - nature.com
Through harmonized procedures and by sharing site-specific brain metrics (for example,
cortical thickness) or aggregated statistical maps, ENIGMA has set the stage for large-scale …

The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex

AO Ceceli, CW Bradberry, RZ Goldstein - Neuropsychopharmacology, 2022 - nature.com
A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

Brain imaging of the cortex in ADHD: a coordinated analysis of large-scale clinical and population-based samples

M Hoogman, R Muetzel, JP Guimaraes… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Neuroimaging studies show structural alterations of various brain regions in
children and adults with attention deficit hyperactivity disorder (ADHD), although …

ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

L Schmaal, E Pozzi, T C. Ho, LS Van Velzen… - Translational …, 2020 - nature.com
A key objective in the field of translational psychiatry over the past few decades has been to
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …

[HTML][HTML] How machine learning is used to study addiction in digital healthcare: A systematic review

B Chhetri, LM Goyal, M Mittal - International Journal of Information …, 2023 - Elsevier
Long-term use of drugs can sometimes result in brain damage that greatly affects a person's
psychology and sometimes become indecent. This paper examines psychological disorders …

Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders: evidence through univariate and multivariate mega-analysis …

N Opel, A Thalamuthu, Y Milaneschi, D Grotegerd… - Molecular …, 2021 - nature.com
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here
we aimed to clarify the relationship between obesity and brain structure using structural MRI …