Objectives The liberalisation of cannabis laws, the increasing availability and potency of
cannabis has renewed concern about the risk of psychosis with cannabis. Methods The …

The persistence of drug taking despite its adverse consequences plays a central role in the
presentation, diagnosis, and impacts of addiction. Eventual recognition and appraisal of …

Neuroimaging has been extensively used to study brain structure and function in individuals
with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over …

Higher educational attainment is observationally associated with lower risk of Alzheimer's
disease. However, the biological mechanisms underpinning this association remain unclear …

Importance Past studies have identified associations between brain macrostructure and
alcohol use behaviors. However, identifying directional associations between these …

There have been dramatic changes worldwide in the attitudes toward and consumption of
recreational and medical cannabis. Cannabinoid receptors, which mediate the actions of …

Introduction Numerous neuroimaging studies of resting‐state functional imaging and voxel‐
based morphometry (VBM) have revealed that patients with substance use disorder (SUD) …

MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …

Addictions are heritable and unfold dynamically across the lifespan. One prominent
neurobiological theory proposes that substance-induced changes in neural circuitry promote …

Background Neuroimaging studies reveal structural and functional including neurochemical
brain abnormalities in individuals with substance use disorders compared to healthy …