The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

Human skin is the largest organ and serves as the first line of defense against environmental
factors. The human microbiota is defined as the total microbial community that coexists in the …

The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

The 16S rRNA gene has been a mainstay of sequence-based bacterial analysis for
decades. However, high-throughput sequencing of the full gene has only recently become a …

Lipid synthesis is necessary for formation of epithelial barriers and homeostasis with
external microbes. An analysis of the response of human keratinocytes to several different …

Functioning as the exterior interface of the human body with the environment, skin acts as a
physical barrier to prevent the invasion of foreign pathogens while providing a home to the …

The skin is a complex and dynamic ecosystem that is inhabited by bacteria, archaea, fungi
and viruses. These microbes—collectively referred to as the skin microbiota—are …

While the commensal bacterium Propionibacterium acnes (P. acnes) is involved in the
maintenance of a healthy skin, it can also act as an opportunistic pathogen in acne vulgaris …

Our understanding of the role of Cutibacterium acnes in the pathophysiology of acne has
recently undergone a paradigm shift: rather than C. acnes hyperproliferation, it is the loss of …