[HTML][HTML] Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation

S Madireddy, S Madireddy - Brain Sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

[HTML][HTML] Epilepsy: Mitochondrial connections to the 'Sacred'disease

WH Moos, DV Faller, IP Glavas, I Kanara, K Kodukula… - Mitochondrion, 2023 - Elsevier
Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …

[HTML][HTML] Phytochemical Screening and In Vitro Evaluation of the Antioxidant Potential of Dichloromethane Extracts of Strychnos henningsii Gilg. and Ficus sycomorus L …

K Wanjala Wafula, J Kiambi Mworia… - The Scientific World …, 2023 - hindawi.com
Medicinal plants are a rich source of antioxidants such as flavonoids, phenols, tannins, and
alkaloids among others and are currently used as alternative and complementary drugs in …

Melatonin protects Kir2. 1 function in an oxidative stress‐related model of aging neuroglia

A Remigante, S Spinelli, P Zuccolini, P Gavazzo… - …, 2023 - Wiley Online Library
Melatonin is a pleiotropic biofactor and an effective antioxidant and free radical scavenger
and, as such, can be protective in oxidative stress‐related brain conditions including …

[HTML][HTML] Understanding Lamotrigine's role in the CNS and possible future evolution

B Costa, N Vale - International Journal of Molecular Sciences, 2023 - mdpi.com
The anti-epileptic drug lamotrigine (LTG) has been widely used to treat various neurological
disorders, including epilepsy and bipolar disorder. However, its precise mechanism of action …

Therapeutic Effect of Levetiracetam Against Thioacetamide-Induced Hepatic Encephalopathy Through Inhibition of Oxidative Stress and Downregulation of NF-κB …

K Amirshahrokhi, M Imani - Inflammation, 2024 - Springer
Hepatic encephalopathy (HE) is a serious brain disorder which associated with neurological
and psychiatric manifestations. Oxidative stress and neuroinflammation and apoptosis play …

Neuronal wires and novel epileptic gene studies: Methods and mechanism of brain network and-Recent update

MS Rajendran, R Prabhakaran, RM Ahalliya… - Human Gene, 2023 - Elsevier
Neurons are simple cell structure of the neuronal system. Brain networks are formed from a
single neuron to highly complex, interconnected neurons (nearly 100 billion). The …

[PDF][PDF] Unexpected Seizure Activity in the Setting of Lamotrigine Toxicity

D Pitter, S Hanley, H Eisa, Y Nene, X Zhou, SE Hanley - Cureus, 2024 - cureus.com
Lamotrigine, a widely utilized broad-spectrum anticonvulsant, is commonly prescribed for
epilepsy management and bipolar mood disorders. Despite its extensive clinical usage …

Use of antiseizure medications during pregnancy and adverse neonatal outcomes

A Lavu - 2024 - mspace.lib.umanitoba.ca
Background: Epilepsy during pregnancy can lead to various adverse health outcomes in
both pregnant people and infants. Furthermore, in-utero exposure to antiseizure medications …

[HTML][HTML] Relationship Between Serum Malondialdehyde (MDA) Levels With Seizure Frequency In Epilepsy Patients With Combination Of Phenytoin And Valproic Acid

A Noegroho, AC Bintoro… - Medica …, 2024 - medicahospitalia.rskariadi.co.id
Background: Oxidative stress is believed to be one of the factors involved in the
pathogenesis of epileptogenic where lipid peroxidation occurs which produces …