Allicin, an antioxidant and neuroprotective agent, ameliorates cognitive impairment

MS Nadeem, I Kazmi, I Ullah, K Muhammad, F Anwar - Antioxidants, 2021 - mdpi.com
Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

Pathological changes within the cerebral vasculature in Alzheimer's disease: New perspectives

RA Fisher, JS Miners, S Love - Brain Pathology, 2022 - Wiley Online Library
Cerebrovascular disease underpins vascular dementia (VaD), but structural and functional
changes to the cerebral vasculature contribute to disease pathology and cognitive decline in …

[HTML][HTML] Alzheimer's disease pathophysiology in the retina

BP Gaire, Y Koronyo, DT Fuchs, H Shi… - Progress in Retinal and …, 2024 - Elsevier
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Detection of retinal changes with optical coherence tomography angiography in mild cognitive impairment and Alzheimer's disease patients: A meta-analysis

J Hui, Y Zhao, S Yu, J Liu, K Chiu, Y Wang - PLoS One, 2021 - journals.plos.org
Objective To assess retinal microvascular network impairments in the eyes of mild cognitive
impairment (MCI) and Alzheimer's disease (AD) patients with optical coherence tomography …

Retinal capillary microvessel morphology changes are associated with vascular damage and dysfunction in cerebral small vessel disease

SJ Wiseman, JF Zhang, C Gray… - Journal of Cerebral …, 2023 - journals.sagepub.com
Cerebral small vessel disease (SVD) is a cause of stroke and dementia. Retinal capillary
microvessels revealed by optical coherence tomography angiography (OCTA) are …

Using a dual-stream attention neural network to characterize mild cognitive impairment based on retinal images

H Gao, S Zhao, G Zheng, X Wang, R Zhao… - Computers in Biology …, 2023 - Elsevier
Mild cognitive impairment (MCI) is a critical transitional stage between normal cognition and
dementia, for which early detection is crucial for timely intervention. Retinal imaging has …

[HTML][HTML] The retina: A window in which to view the pathogenesis of Alzheimer's disease

J Zhang, L Shi, Y Shen - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most familiar type of dementia affecting elderly populations
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …

The eye as a diagnostic tool for Alzheimer's disease

A Hussain, Z Sheikh, M Subramanian - Life, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder impacting cognition,
function, and behavior in the elderly population. While there are currently no disease …

Alzheimer's disease: new insight in assessing of amyloid plaques morphologies using multifractal geometry based on Naive Bayes optimized by random forest …

E Amin, YM Elgammal, MA Zahran, MM Abdelsalam - Scientific Reports, 2023 - nature.com
Alzheimer's disease (AD) is a physical illness, which damages a person's brain; it is the most
common cause of dementia. AD can be characterized by the formation of amyloid-beta (Aβ) …

Retinal microvascular changes in mild cognitive impairment and Alzheimer's disease: a systematic review, meta-analysis, and meta-regression

TC Yeh, CT Kuo, YB Chou - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Background The remarkable increase in prevalence and significant morbidity of
neurodegenerative diseases pose a tremendous burden for the health care system …