Melatonin modulates tumor metabolism and mitigates metastasis
Introduction Melatonin, originally isolated from the mammalian pineal gland, was
subsequently identified in many animal cell types and in plants. While melatonin was …
subsequently identified in many animal cell types and in plants. While melatonin was …
[HTML][HTML] Melatonin, BAG-1 and cortisol circadian interactions in tumor pathogenesis and patterned immune responses
G Anderson - Exploration of targeted anti-tumor therapy, 2023 - ncbi.nlm.nih.gov
A dysregulated circadian rhythm is significantly associated with cancer risk, as is aging. Both
aging and circadian dysregulation show suppressed pineal melatonin, which is indicated in …
aging and circadian dysregulation show suppressed pineal melatonin, which is indicated in …
In Situ Piezoelectric‐Catalytic Anti‐Inflammation Promotes the Rehabilitation of Acute Spinal Cord Injury in Synergy
Relieving inflammation via scavenging toxic reactive oxygen species (ROS) during the acute
phase of spinal cord injury (SCI) proves to be an effective strategy to mitigate secondary …
phase of spinal cord injury (SCI) proves to be an effective strategy to mitigate secondary …
[HTML][HTML] Why are aging and stress associated with dementia, cancer, and other diverse medical conditions? Role of pineal melatonin interactions with the HPA axis in …
G Anderson - Melatonin Research, 2023 - melaonin-research.com
Pineal melatonin and the cortisol awakening response (CAR) are integral aspects of the
circadian rhythm. Pineal melatonin release during sleep is proposed to optimize …
circadian rhythm. Pineal melatonin release during sleep is proposed to optimize …
[HTML][HTML] Polycystic ovary syndrome pathophysiology: integrating systemic, CNS and circadian processes
G Anderson - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
The conceptualization of polycystic ovary syndrome (PCOS) has primarily focused on
hormonal alterations driven by changes within the hypothalamus and ovarian granulosa …
hormonal alterations driven by changes within the hypothalamus and ovarian granulosa …
Combination Therapy with N-Acetylserotonin and Aflibercept Activated the Akt/Nrf2 Pathway to Inhibit Apoptosis and Oxidative Stress in Rats with Retinal Ischemia …
J Zhang, Z Zhang, L Jiang, S He, X Long… - Current Eye …, 2024 - Taylor & Francis
Purpose N-acetylserotonin (NAS) can reduce retinal ischemia–reperfusion injury (RIRI) by
inhibiting the TLR4/NF-κB/NLRP3 signaling pathway. Aflibercept is an anti-VEGF drug used …
inhibiting the TLR4/NF-κB/NLRP3 signaling pathway. Aflibercept is an anti-VEGF drug used …
Role of carboxylesterase and arylacetamide deacetylase in drug metabolism, physiology, and pathology
M Nagaoka, Y Sakai, M Nakajima, T Fukami - Biochemical Pharmacology, 2024 - Elsevier
Abstract Carboxylesterases (CES1 and CES2) and arylacetamide deacetylase (AADAC),
which are expressed primarily in the liver and/or gastrointestinal tract, hydrolyze drugs …
which are expressed primarily in the liver and/or gastrointestinal tract, hydrolyze drugs …
Sex-specific metabolic dysregulation in digestive glands of green mussels following exposure to triazophos
L Zhang, W Sun, Z Zhang, F Tian, H Chen - Pesticide Biochemistry and …, 2023 - Elsevier
As a ubiquitous environmental pollutant in China, triazophos (TP) is known to have
neurotoxicity, oxidative stress, and reproductive toxicity to mussels. To investigate the …
neurotoxicity, oxidative stress, and reproductive toxicity to mussels. To investigate the …
[HTML][HTML] N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-κB pathway in rats
YZ Zhao, XN Zhang, Y Yin, PL Xiao, M Gao… - International Journal …, 2024 - ncbi.nlm.nih.gov
AIM To observe the effects of N-acetylserotonin (NAS) administration on retinal ischemia-
reperfusion (RIR) injury in rats and explore the underlying mechanisms involving the high …
reperfusion (RIR) injury in rats and explore the underlying mechanisms involving the high …