Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Introduction The 18-kDa translocator protein (TSPO) is increasingly recognized as a
molecular target for PET imaging of inflammatory responses in various central nervous …

Microglial activation plays central roles in neuroinflammatory and neurodegenerative
diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein …

Abstract Background Coronavirus disease 2019 (COVID-19) patients initially develop
respiratory symptoms, but they may also suffer from neurological symptoms. People with …

Efficient treatment of stress-related disorders, such as depression, is still a major challenge.
The onset of antidepressant drug action is generally quite slow, while the anxiolytic action of …

The bone marrow in the skull is important for shaping immune responses in the brain and
meninges, but its molecular makeup among bones and relevance in human diseases …

The COVID-19 pandemic caused by SARS-CoV-2 has triggered a consequential public
health crisis of post-acute sequelae of COVID-19 (PASC), sometimes referred to as long …

Bipolar disorder (BD) is a severe and multifactorial disease, with onset usually in young
adulthood, which follows a progressive course throughout life. Replicated epidemiological …

The pathophysiological underpinnings of critically disrupted brain connectomes resulting in
coma are poorly understood. Inflammation is potentially an important but still undervalued …

Macrophage is a kind of immune cell and performs multiple functions including pathogen
phagocytosis, antigen presentation and tissue remodeling. To fulfill their functionally distinct …