Programming cytomegalovirus as an HIV vaccine

LJ Picker, JD Lifson, M Gale, SG Hansen, K Früh - Trends in Immunology, 2023 - cell.com
The initial development of cytomegalovirus (CMV) as a vaccine vector for HIV/simian
immunodeficiency virus (SIV) was predicated on its potential to pre-position high-frequency …

Mucosal immune system of the gastrointestinal tract: maintaining balance between the good and the bad

B Ahluwalia, MK Magnusson… - Scandinavian journal of …, 2017 - Taylor & Francis
The gastrointestinal tract (GI tract) is a unique organ inhabited by a range of commensal
microbes, while also being exposed to an overwhelming load of antigens in the form of …

The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys

L Jiao, Y Yang, W Yu, Y Zhao, H Long, J Gao… - Signal transduction and …, 2021 - nature.com
Neurological manifestations are frequently reported in the COVID-19 patients.
Neuromechanism of SARS-CoV-2 remains to be elucidated. In this study, we explored the …

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow

C Daussy, F Faure, K Mayol, S Viel… - Journal of Experimental …, 2014 - rupress.org
Trail+ DX5− Eomes− natural killer (NK) cells arise in the mouse fetal liver and persist in the
adult liver. Their relationships with Trail− DX5+ NK cells remain controversial. We generated …

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

S Tripathi, VRMT Balasubramaniam, JA Brown… - PLoS …, 2017 - journals.plos.org
Zika virus (ZIKV) is a mosquito borne flavivirus, which was a neglected tropical pathogen
until it emerged and spread across the Pacific Area and the Americas, causing large human …

Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
Hypercytokinemia, found in SARS-CoV-2 infection, contributes to multiple organ
dysfunctions with acute respiratory distress syndrome, shock etc. The aim of this study was …

Цитокины в патогенезе и лечении заболеваний человека

АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

[HTML][HTML] Type I interferons and natural killer cell regulation in cancer

L Müller, P Aigner, D Stoiber - Frontiers in immunology, 2017 - frontiersin.org
Type I interferons (IFNs) are known to mediate antitumor effects against several tumor types
and have therefore been commonly used in clinical anticancer treatment. However, how IFN …

Treatment with soluble CD24 attenuates COVID-19-associated systemic immunopathology

NJ Song, C Allen, AE Vilgelm, BP Riesenberg… - Journal of Hematology & …, 2022 - Springer
Abstract Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
causes coronavirus disease 2019 (COVID-19) through direct lysis of infected lung epithelial …

[HTML][HTML] Flow-mediated susceptibility and molecular response of cerebral endothelia to SARS-CoV-2 infection

N Kaneko, S Satta, Y Komuro, SD Muthukrishnan… - Stroke, 2021 - journals.lww.com
Background and Purpose: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
infection is associated with an increased rate of cerebrovascular events including ischemic …