[HTML][HTML] Computer-Aided Screening of Phytoconstituents from Ocimum tenuiflorum against Diabetes Mellitus Targeting DPP4 Inhibition: A Combination of Molecular …
Diabetes mellitus is a major global health concern in the current scenario which is chiefly
characterized by the rise in blood sugar levels or hyperglycemia. In the context, DPP4 …
characterized by the rise in blood sugar levels or hyperglycemia. In the context, DPP4 …
[HTML][HTML] Integrated network pharmacology and molecular modeling approach for the discovery of novel potential MAPK3 inhibitors from whole green jackfruit flour …
The current study investigates the effectiveness of phytocompounds from the whole green
jackfruit flour methanol extract (JME) against obesity-linked diabetes mellitus using …
jackfruit flour methanol extract (JME) against obesity-linked diabetes mellitus using …
[HTML][HTML] Phyto-Computational Intervention of Diabetes Mellitus at Multiple Stages Using Isoeugenol from Ocimum tenuiflorum: A Combination of Pharmacokinetics …
In the present study, the anti-diabetic potential of Ocimum tenuiflorum was investigated
using computational techniques for α-glucosidase, α-amylase, aldose reductase, and …
using computational techniques for α-glucosidase, α-amylase, aldose reductase, and …
Molecular insights into the in silico discovery of corilagin from Terminalia chebula as a potential dual inhibitor of SARS-CoV-2 structural proteins
The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic proteins
of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its …
of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its …
[HTML][HTML] Multiprotein inhibitory effect of dietary polyphenol rutin from whole green jackfruit flour targeting different stages of diabetes mellitus: defining a bio …
The anti-diabetic potential of whole unripe jackfruit (peel with pulp, flake, and seed) was
investigated using inhibitory assays for α-glucosidase, α-amylase, aldose reductase, and …
investigated using inhibitory assays for α-glucosidase, α-amylase, aldose reductase, and …
[HTML][HTML] Ten years milestones in xanthine oxidase inhibitors discovery: febuxostat-based inhibitors trends, bifunctional derivatives, and automatized screening assays
MFS de Abreu, CA Wegermann, MS Ceroullo… - Organics, 2022 - mdpi.com
Xanthine oxidase (XO) is an enzyme involved in the oxidative process of hypoxanthine and
xanthine to uric acid (UA). This process also produces reactive oxygen species (ROS) as …
xanthine to uric acid (UA). This process also produces reactive oxygen species (ROS) as …
Inhibitory effect of gallic acid from Thunbergia mysorensis against α-glucosidase, α-amylase, aldose reductase and their interaction: Inhibition kinetics and molecular …
In this exploration, we assessed the antihyperglycaemic properties of methanol extract of
flowers of Thunbergia mysorensis (MeT) against α-glucosidase, α-amylase and aldose …
flowers of Thunbergia mysorensis (MeT) against α-glucosidase, α-amylase and aldose …
[HTML][HTML] Inhibition of carbohydrate hydrolyzing enzymes by a potential probiotic Levilactobacillus brevis RAMULAB49 isolated from fermented Ananas comosus
RM Martiz, C Kumari VB, SS Huligere… - Frontiers in …, 2023 - frontiersin.org
The research aimed to explore the potential probiotic characteristics of Levilactobacillus
brevis RAMULAB49, a strain of lactic acid bacteria (LAB) isolated from fermented pineapple …
brevis RAMULAB49, a strain of lactic acid bacteria (LAB) isolated from fermented pineapple …
Design, synthesis, characterization, docking studies of novel 4-phenyl acrylamide-1, 3-thiazole derivatives as anti-inflammatory and anti-ulcer agents
A great extent of nitrogen containing heterocyclic moiety comprising sulfur atom is
recognized as a valuable combination of therapeutics in medicinal chemistry. In particular …
recognized as a valuable combination of therapeutics in medicinal chemistry. In particular …
Design, one-pot synthesis, in silico ADMET prediction and molecular docking of novel triazolyl thiadiazine and thiazole derivatives with evaluation of antimicrobial …
RE Khidre, E Sabry, AF El-Sayed, AA Sediek - Journal of the Iranian …, 2023 - Springer
A facile one pot multi-component synthesis of novel 1, 3, 4-thiadiazine and thiazole
derivatives from the reaction of (methyl-1-(p-tolyl)-1 H-1, 2, 3-triazol-4-yl) ethan-1-one …
derivatives from the reaction of (methyl-1-(p-tolyl)-1 H-1, 2, 3-triazol-4-yl) ethan-1-one …