[HTML][HTML] A systematic literature review on obesity: Understanding the causes & consequences of obesity and reviewing various machine learning approaches used to …

M Safaei, EA Sundararajan, M Driss, W Boulila… - Computers in biology …, 2021 - Elsevier
Obesity is considered a principal public health concern and ranked as the fifth foremost
reason for death globally. Overweight and obesity are one of the main lifestyle illnesses that …

Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

J Ren, NN Wu, S Wang, JR Sowers… - Physiological …, 2021 - journals.physiology.org
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Myosteatosis in the context of skeletal muscle function deficit: an interdisciplinary workshop at the National Institute on Aging

R Correa-de-Araujo, O Addison, I Miljkovic… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …

Pathophysiological molecular mechanisms of obesity: a link between MAFLD and NASH with cardiovascular diseases

J Gutiérrez-Cuevas, A Santos… - International Journal of …, 2021 - mdpi.com
Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …

Intestinal barrier and permeability in health, obesity and NAFLD

P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

Why primary obesity is a disease?

A De Lorenzo, S Gratteri, P Gualtieri… - Journal of translational …, 2019 - Springer
Obesity must be considered a real pathology. In the world wide, obesity represent one of the
major public health issue associated with increased morbidity and mortality. Overweight or …

Relevance of leptin and other adipokines in obesity-associated cardiovascular risk

MF Landecho, C Tuero, V Valentí, I Bilbao… - Nutrients, 2019 - mdpi.com
Obesity, which is a worldwide epidemic, confers increased risk for multiple serious
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

L Liberale, F Montecucco, JC Tardif… - European heart …, 2020 - academic.oup.com
The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …

Relevance of body composition in phenotyping the obesities

L Salmón-Gómez, V Catalán, G Frühbeck… - Reviews in Endocrine …, 2023 - Springer
Obesity is the most extended metabolic alteration worldwide increasing the risk for the
development of cardiometabolic alterations such as type 2 diabetes, hypertension, and …

Mitochondria and reactive oxygen species in aging and age-related diseases

C Giorgi, S Marchi, ICM Simoes, Z Ren… - International review of …, 2018 - Elsevier
Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …