The decision to pursue one's desire for children is a basic human right. For transgender and
gender-diverse (TGD) people, gender-affirming care may alter the possibilities to fulfill one's …

BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

Curative therapy for sickle cell disease (SCD) currently requires gonadotoxic conditioning
that can impair future fertility. Fertility outcomes after curative therapy are likely affected by …

Due to the growing number of young patients at risk of germ cell loss, there is a need to
preserve spermatogonial stem cells for patients who are not able to bank spermatozoa …

The deleterious effects of chemical or non-chemical endocrine disruptors (EDs) on male
fertility potential is well documented but still not fully elucidated. For example, the detection …

Fertility restoration in patients that survived a hematological cancer during childhood is a
core part of their care pathway. Nonetheless, there might be a risk of contamination of the …

STUDY QUESTION Twenty years after the inception of the first fertility preservation
programme for pre-pubertal boys, what are the current international practices with regard to …

Avascular transplantation of frozen–thawed testicular tissue fragments represents a potential
future technique for fertility restoration in boys with cancer. A significant loss of …

Fertility preservation in prepubertal boys is a matter that has been gaining ground fast during
the past 20 years. As the life expectancy for childhood cancer survivors continues to …