Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Neurobiology of addiction: An integrative review

A Goodman - Biochemical pharmacology, 2008 - Elsevier
Evidence that psychoactive substance use disorders, bulimia nervosa, pathological
gambling, and sexual addiction share an underlying biopsychological process is …

Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice

S Kim, Y Jin, Y Choi, T Park - Biochemical pharmacology, 2011 - Elsevier
Resveratrol is a natural polyphenolic stilbene derivative found in a variety of edible fruits,
including nuts, berries, and grape skin. Although resveratrol has been suggested to improve …

The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

[HTML][HTML] Biology of obesity: lessons from animal models of obesity

K Kanasaki, D Koya - BioMed Research International, 2011 - hindawi.com
Obesity is an epidemic problem in the world and is associated with several health problems,
including diabetes, cardiovascular disease, respiratory failure, muscle weakness, and …

Hypothalamic control of energy balance: different peptides, different functions

SF Leibowitz, KE Wortley - Peptides, 2004 - Elsevier
Energy balance is maintained via a homeostatic system involving both the brain and the
periphery. A key component of this system is the hypothalamus. Over the past two decades …

[PDF][PDF] Animal models of obesity

J Speakman, C Hambly, S Mitchell, E Krol - Obesity Reviews, 2007 - researchgate.net
Background Obesity stems from a prolonged imbalance between the levels of energy intake
and expenditure, with the resultant surplus being stored as body lipids. Our understanding of …

[PDF][PDF] Suppression of insulin production and secretion by a decretin hormone

RW Alfa, S Park, KR Skelly, G Poffenberger, N Jain… - Cell metabolism, 2015 - cell.com
Decretins, hormones induced by fasting that suppress insulin production and secretion,
have been postulated from classical human metabolic studies. From genetic screens, we …

Neuropeptides and obesity

B Beck - Nutrition, 2000 - Elsevier
This review focuses on the expression, content, and release of neuropeptides and on their
role in the development of obesity in animal models with single-gene mutations. The …

Restricted distribution of galanin receptor 3 (GalR3) mRNA in the adult rat central nervous system

F Mennicken, C Hoffert, M Pelletier, S Ahmad… - Journal of chemical …, 2002 - Elsevier
Recent molecular cloning studies have established the existence of a third rat galanin
receptor subtype, GalR3, however its precise distribution in the mammalian central nervous …