Obesity is a major global health problem and predisposes individuals to several
comorbidities that can affect life expectancy. Interventions based on lifestyle modification (for …

Abstract “Food addiction” has become a focus of interest for researchers attempting to
explain certain processes and/or behaviors that may contribute to the development of …

Food is a potent natural reward and food intake is a complex process. Reward and
gratification associated with food consumption leads to dopamine (DA) production, which in …

Each of the macronutrients—carbohydrate, protein, and fat—has a unique set of properties
that influences health, but all are a source of energy. The optimal balance of their …

Accumulated preclinical literature demonstrates that hypothalamic inflammation and gliosis
are underlying causal components of diet-induced obesity in rodent models. This review …

Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …

Background Nutrition is a prerequisite for health; yet, there is no special nutritional
assessment or guidance for drug and alcohol dependent individuals, despite the fact that …

Evaluating external and internal stimuli is critical to survival. Potentially tissue-damaging
conditions generate sensory experiences that the organism must respond to in an …

Here we review recent advances that identify a role for the central ghrelin signalling system
in reward from both natural rewards (such as food) and artificial rewards (that include …

The neuronal circuitry underlying the complex relationship between stress, mood and food
intake are slowly being unravelled and several studies suggest a key role herein for the …