Surgical options for patients with early-stage breast cancer and pathogenic germline variants: an oncologist perspectives
H Abdel-Razeq - Frontiers in Oncology, 2023 - frontiersin.org
Breast cancer continues to be the most common cancer diagnosed among women
worldwide. Family history of breast cancer is frequently encountered, and 5-15% of patients …
worldwide. Family history of breast cancer is frequently encountered, and 5-15% of patients …
Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets
S Zhang, X Xiao, Y Yi, X Wang, L Zhu, Y Shen… - … and Targeted Therapy, 2024 - nature.com
Tumorigenesis is a multistep process, with oncogenic mutations in a normal cell conferring
clonal advantage as the initial event. However, despite pervasive somatic mutations and …
clonal advantage as the initial event. However, despite pervasive somatic mutations and …
Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Background: Previous studies have demonstrated that incorporating a polygenic risk score
(PRS) to existing risk prediction models for breast cancer improves model fit, but to …
(PRS) to existing risk prediction models for breast cancer improves model fit, but to …
[HTML][HTML] Polygenic Risk Score (PRS) Combined with NGS Panel Testing Increases Accuracy in Hereditary Breast Cancer Risk Estimation
N Tsoulos, E Papadopoulou, K Agiannitopoulos… - Diagnostics, 2024 - mdpi.com
Breast cancer (BC) is the most prominent tumor type among women, accounting for 32% of
newly diagnosed cancer cases. BC risk factors include inherited germline pathogenic gene …
newly diagnosed cancer cases. BC risk factors include inherited germline pathogenic gene …
A combined risk model shows viability for personalized breast cancer risk assessment in the Indonesian population
B Rabbani, SG Tanu, KN Ramanto, J Audrienna… - medRxiv, 2023 - medrxiv.org
Breast cancer remains a significant concern worldwide, with a rising incidence in Indonesia.
This study aims to evaluate the applicability of risk-based screening approaches in the …
This study aims to evaluate the applicability of risk-based screening approaches in the …