Role of extracellular vesicles in intercellular communication during reproduction

K Godakumara, K Dissanayake… - … in Domestic Animals, 2022 - Wiley Online Library
The mammalian reproduction is a process of controlled cellular growth and development
regulated by constant communication between the gametes, the subsequent embryo and …

Omics insights into extracellular vesicles in embryo implantation and their therapeutic utility

QH Poh, A Rai, LA Salamonsen, DW Greening - Proteomics, 2023 - Wiley Online Library
Implantation success relies on intricate interplay between the developing embryo and the
maternal endometrium. Extracellular vesicles (EVs) represent an important player of this …

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

KC Pavani, T Meese, OB Pascottini… - Proceedings of the …, 2022 - National Acad Sciences
Extracellular vesicles (EVs) and their cargo microRNAs (miRNAs) are important regulators of
embryo development to the blastocyst stage and beyond. Before implantation can take …

The extracellular vesicles proteome of endometrial cells simulating the receptive menstrual phase differs from that of endometrial cells simulating the non-receptive …

AR Hart, NLA Khan, K Dissanayake, K Godakumara… - Biomolecules, 2023 - mdpi.com
Successful embryo implantation into a receptive endometrium requires mutual endometrial-
embryo communication. Recently, the function of extracellular vehicles (EVs) in cell-to-cell …

Extracellular vesicle research in reproductive science: Paving the way for clinical achievements

E Aleksejeva, N Zarovni, K Dissanayake… - Biology of …, 2022 - academic.oup.com
Mammalian conception involves a multitude of reciprocal interactions via a molecular
dialogue between mother and conceptus. Extracellular vesicles (EVs) are secreted …

The role of extracellular vesicles in endometrial receptivity and their potential in reproductive therapeutics and diagnosis

AR Hart, NLA Khan, K Godakumara, K Dissanayake… - Reproductive …, 2022 - Elsevier
abstract Extracellular vesicles (EVs) are small, nanometre sized, membrane-enclosed
structures released by cells and are thought to be crucial in cellular communication. The …

Extracellular vesicles in mammalian reproduction: a review

EL Munoz, FB Fuentes, RN Felmer, M Yeste, ME Arias - Zygote, 2022 - cambridge.org
Over the last decades, extracellular vesicles (EVs) have been found to be implicated in a
complex universal mechanism of communication between different cell types. EVs are …

Transcriptome regulation of extracellular vesicles derived from porcine uterine flushing fluids during peri-implantation on endometrial epithelial cells and embryonic …

R Hua, Q Liu, W Lian, D Gao, C Huang, M Lei - Gene, 2022 - Elsevier
The extracellular vesicles (EVs) in uterine fluids play a vital role in embryo implantation by
mediating intrauterine communication between conceptus and maternal endometrium in …

Embryo-maternal communication mediated by extracellular vesicles in the early stages of embryonic development is modified by in vitro conditions

C Aguilera, YS Wong, MA Gutierrez-Reinoso… - Theriogenology, 2024 - Elsevier
Extracellular vesicles (EVs) have become important in embryo-maternal communication
during early development. The aim of this study was to evaluate the effect of an in vitro …

The role of extracellular vesicles in intercellular communication in human reproduction

J Gonzalez Fernandez, J Moncayo Arlandi… - Clinical …, 2023 - portlandpress.com
Embryo–maternal cross-talk has emerged as a vitally important process for embryo
development and implantation, which is driven by secreted factors and extracellular vesicles …