All roads lead to directional cell migration
A Shellard, R Mayor - Trends in cell biology, 2020 - cell.com
Directional cell migration normally relies on a variety of external signals, such as chemical,
mechanical, or electrical, which instruct cells in which direction to move. Many of the major …
mechanical, or electrical, which instruct cells in which direction to move. Many of the major …
Microtubule targeting agents in disease: classic drugs, novel roles
L Wordeman, JJ Vicente - Cancers, 2021 - mdpi.com
Simple Summary Microtubules (MTs) are highly conserved proteins present in all eukaryotic
organisms. They form the cell cytoskeleton, and its function is essential for a large number of …
organisms. They form the cell cytoskeleton, and its function is essential for a large number of …
Unravelling cell migration: defining movement from the cell surface
F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
Public RNA-seq data-based identification and functional analyses reveal that MXRA5 retains proliferative and migratory abilities of dental pulp stem cells
K Yoshida, S Suzuki, H Yuan, A Sato… - Scientific Reports, 2023 - nature.com
Dental pulp stem cells (DPSC) usually remain quiescent in the dental pulp tissue; however,
once the dental pulp tissue is injured, DPSCs potently proliferate and migrate into the injury …
once the dental pulp tissue is injured, DPSCs potently proliferate and migrate into the injury …
Syndecan-4 in tumor cell motility
A Keller-Pinter, S Gyulai-Nagy, D Becsky, L Dux… - Cancers, 2021 - mdpi.com
Simple Summary Cell migration is crucial fReaor metastasis formation and a hallmark of
malignancy. The primary cause of high mortality among oncology patients is the ability of …
malignancy. The primary cause of high mortality among oncology patients is the ability of …
Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
Y Zhang, L Sun, H Li, L Ai, Q Ma, X Qiao, J Yang… - Elife, 2022 - elifesciences.org
Background: Integrin family are known as key gears in focal adhesion for triple-negative
breast cancer (TNBC) metastasis. However, the integrin independent factor TLN1 remains …
breast cancer (TNBC) metastasis. However, the integrin independent factor TLN1 remains …
Role of intermediate filaments in blood–brain barrier in health and disease
E Bayir, A Sendemir - Cells, 2021 - mdpi.com
The blood–brain barrier (BBB) is a highly selective cellular monolayer unique to the
microvasculature of the central nervous system (CNS), and it mediates the communication of …
microvasculature of the central nervous system (CNS), and it mediates the communication of …
Mitotic centromere-associated kinesin (MCAK/KIF2C) regulates cell migration and invasion by modulating microtubule dynamics and focal adhesion turnover
HH Moon, NN Kreis, A Friemel, S Roth, D Schulte… - Cancers, 2021 - mdpi.com
Simple Summary The microtubule (MT) cytoskeleton is a crucial factor for organized cell
motility and migration of cancer as well as benign cells. Mitotic centromere-associated …
motility and migration of cancer as well as benign cells. Mitotic centromere-associated …
Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation
Microtubules (MTs) and their associated proteins play essential roles in maintaining cell
structure, organelle transport, cell motility, and cell division. Two motors, kinesin and …
structure, organelle transport, cell motility, and cell division. Two motors, kinesin and …
Intrinsic mechanisms regulating neuronal migration in the postnatal brain
C Bressan, A Saghatelyan - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Neuronal migration is a fundamental brain development process that allows cells to move
from their birthplaces to their sites of integration. Although neuronal migration largely ceases …
from their birthplaces to their sites of integration. Although neuronal migration largely ceases …