Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Peripheral arterial disease (PAD) is very frequent in diabetics, and it increases with age.
Foot examination contributes poorly to diagnosis of PAD. The ankle-brachial index (ABI) …

Background We aimed to characterize the occurrence of major adverse cardiovascular and
limb events (MACE and MALE) among patients with peripheral artery disease (PAD) …

BACKGROUND: Both statins and ezetimibe lower LDL-C, but ezetimibe's effect on
atherosclerosis is controversial. We hypothesized that lowering LDL-C cholesterol by adding …

Background We investigated whether disease location influences survival in patients with
peripheral arterial disease. Methods and Results Patients (n= 12 731; mean age, 67.5±12.7 …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Abstract Background and Aims Patients undergoing revascularization for lower extremity
arterial disease (LEAD) may face a higher risk of mortality than those with coronary artery …

Background—Epidemiology data for lower-extremity arterial thromboembolism (LET) are
limited and may result from either acute limb ischemia or an acute exacerbation of critical …

Science has made enormous achievements for our understanding of the world and for
everyday life: we now know that we live on a spherical planet of the solar system, we …

Patients with peripheral artery disease (PAD) have an increased risk of cardiovascular (CV)
and limb events, but the disease is frequently underdiagnosed and treatment options are …