The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …

Mental health researchers and clinicians have long sought answers to the question “What
works for whom?” The goal of precision medicine is to provide evidence-based answers to …

Importance Major depressive disorder (MDD) has been linked to imbalanced
communication among large-scale brain networks, as reflected by abnormal resting-state …

Major depressive disorder (MDD) affects multiple large-scale functional networks in the
brain, which has initiated a large number of studies on resting-state functional connectivity in …

Depression is linked to deficits in cognitive control and a host of other cognitive impairments
arise as a consequence of these deficits. Despite of their important role in depression, there …

A study with low statistical power has a reduced chance of detecting a true effect, but it is
less well appreciated that low power also reduces the likelihood that a statistically significant …

Uncertainty about a possible future threat disrupts our ability to avoid it or to mitigate its
negative impact and thus results in anxiety. Here, we focus the broad literature on the …

In patients with major depressive disorder or bipolar disorder, abnormalities in excitatory
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …

Objective: Repetitive transcranial magnetic stimulation (rTMS) protocols increasingly use
subgenual anterior cingulate cortex (sgACC) functional connectivity to individualize …

Both psychedelics and meditation exert profound modulatory effects on consciousness,
perception and cognition, but their combined, possibly synergistic effects on neurobiology …