Background Benzodiazepine misuse is a growing public health problem, with increases in
benzodiazepine-related overdose deaths and emergency room visits in recent years …

Benzodiazepines have been in use for over half a century. While they remain highly
prescribed, their unfavorable side-effect profile and abuse liability motivated a search for …

The American Psychiatric Association Practice Guideline for the Treatment of Patients With
Schizophrenia seeks to reduce these substantial psychosocial and public health …

This British Association for Psychopharmacology guideline replaces the original version
published in 2010, and contains updated information and recommendations. A consensus …

In September 2020, the US Food and Drug Administration (FDA) announced an anticipated
update to the boxed warning on all benzodiazepines to explicitly “address the serious risks …

Background Many strategies aimed at deprescribing benzodiazepine receptor agonists
(BZRA) in older adults have already been evaluated with various success rates. There is so …

Abstract Coronavirus disease 2019 (COVID-19) had deleterious effects on patients with
mental health problems and several studies have shown a spike in the rates of depression …

Importance Although overall rates of opioid use have been plateauing, coprescriptions of
benzodiazepines and opioids have increased greatly in recent years. It is unknown whether …

The first hypnotic barbiturate, barbital, was introduced into clinical practice in 1903, followed
by phenobarbital in 1912. 1 In subsequent years, multiple barbiturates were synthesized …

As tranquilizers, benzodiazepines have a wide range of clinical uses. Recently, there has
been a significant rise in the number of novel psychoactive substances, including designer …