[HTML][HTML] Intravenous levothyroxine for unstable brain-dead heart donors
R Dhar, GF Marklin, WD Klinkenberg… - … England Journal of …, 2023 - Mass Medical Soc
Background Hemodynamic instability and myocardial dysfunction are major factors
preventing the transplantation of hearts from organ donors after brain death. Intravenous …
preventing the transplantation of hearts from organ donors after brain death. Intravenous …
Efficacy and safety of triiodothyronine treatment in cardiac surgery or cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
M Tharmapoopathy, A Thavarajah, RPW Kenny… - Thyroid, 2022 - liebertpub.com
Background: Low levels of the active thyroid hormone triiodothyronine (T3) in cardiac
patients are associated with worse outcomes. The aim of this analysis was to assess if T3 …
patients are associated with worse outcomes. The aim of this analysis was to assess if T3 …
Novel uses of thyroid hormones in cardiovascular conditions
S Razvi - Endocrine, 2019 - Springer
Thyroid hormone levels are reduced in cardiovascular diseases and this phenomenon is
associated with worse outcomes. It is unclear whether the changes in thyroid hormone …
associated with worse outcomes. It is unclear whether the changes in thyroid hormone …
Donor heart selection: Evidence-based guidelines for providers
H Copeland, I Knezevic, DA Baran, V Rao… - The Journal of Heart and …, 2023 - Elsevier
The proposed donor heart selection guidelines provide evidence-based and expert-
consensus recommendations for the selection of donor hearts following brain death. These …
consensus recommendations for the selection of donor hearts following brain death. These …
Management of the neurologically deceased organ donor: a Canadian clinical practice guideline
IM Ball, L Hornby, B Rochwerg, MJ Weiss, C Gillrie… - Cmaj, 2020 - Can Med Assoc
This clinical practice guideline is intended for use in the care of both neurologically
deceased adult and pediatric potential organ donors. We based our recommendations on …
deceased adult and pediatric potential organ donors. We based our recommendations on …
Donor thyroid hormone therapy and heart transplantation outcomes: ISHLT transplant registry analysis
Y Peled, E Ram, R Klempfner, J Lavee… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Donor thyroid hormone (TH) supplementation therapy is widely used.
Recent reports suggested an increased risk of graft dysfunction in heart transplant (HTx) …
Recent reports suggested an increased risk of graft dysfunction in heart transplant (HTx) …
A randomized trial comparing triiodothyronine (T3) with thyroxine (T4) for hemodynamically unstable brain‐dead organ donors
R Dhar, E Stahlschmidt, Y Yan… - Clinical …, 2019 - Wiley Online Library
Rationale Brain‐dead (BD) organ donors frequently exhibit hemodynamic instability and/or
reversible cardiac dysfunction. Retrospective studies have suggested that thyroid hormone …
reversible cardiac dysfunction. Retrospective studies have suggested that thyroid hormone …
A randomized trial of intravenous thyroxine for brain-dead organ donors with impaired cardiac function
R Dhar, E Stahlschmidt… - Progress in …, 2020 - journals.sagepub.com
Rationale: Brain death (BD) precipitates cardiac dysfunction impairing the ability to
transplant hearts from eligible organ donors. Retrospective studies have suggested that …
transplant hearts from eligible organ donors. Retrospective studies have suggested that …
Donor thyroid hormone therapy is associated with an increased risk of graft dysfunction after heart transplantation
Y Peled, J Lavee, Y Kassif, M Arad… - Clinical …, 2020 - Wiley Online Library
Objective Heart transplantation (HT) is uniquely associated with the potential impact of
thyroid hormone therapy at three intersecting levels—donor, operation, and recipient. We …
thyroid hormone therapy at three intersecting levels—donor, operation, and recipient. We …
Thyroid hormone resuscitation after brain death in potential organ donors: a primer for neurocritical care providers and narrative review of the literature
IA Buchanan, VA Mehta - Clinical Neurology and Neurosurgery, 2018 - Elsevier
Solid organ transplantation has become a mainstay in the contemporary management of
end-stage organ failures fueled by advances in immunosuppression, intensive care and …
end-stage organ failures fueled by advances in immunosuppression, intensive care and …