Bisoprolol and nebivolol are highly selective β1-adrenoceptor antagonists, with clinical
indications in many countries within the management of heart failure with reduced left …

Dyslipidemia is the most fundamental risk factor for atherosclerotic cardiovascular disease
(ASCVD). In clinical practice, many commonly prescribed medications can alter the patient's …

Blood pressure management in hypertensive patients with metabolic abnormalities is
challenging, since many of the antihypertensive drugs adversely affect metabolism. Besides …

Background Beta arrestins had been known as intracellular adaptors that uncouple and
inactivate the G protein-coupled receptors that they interact with. Their roles as signal …

This review provides a systematic overview of the influence of the third generation beta-
adrenoceptor antagonists on vascular and/or endothelial function at a cellular level as well …

According to the most recent international guidelines, β-blockers maintain a central role in
the management of hypertension, being recommended at any treatment step when there is a …

Aims To assess whether nursing home (NH) residents with type 2 diabetes mellitus (T2D)
preferentially received “T2D‐friendly”(vs “T2D‐unfriendly”) β‐blockers after acute myocardial …

Background Discharge β-blocker prescription after myocardial infarction (MI) is
recommended for all eligible patients. Numerous β-blocker choices are presently available …

Background: The pleiotropic effects of hypotensive drugs should always be taken into
consideration. There is limited data on the effect of such drugs on reducing global …

Despite substantial progress in understanding the complex pathophysiology, hypertension
remains a serious public health challenge affecting over 1.2 billion adults aged 30–79 years …