Expert consensus and evidence-based recommendations for the assessment of flow-mediated dilation in humans

DHJ Thijssen, RM Bruno, ACCM van Mil… - European heart …, 2019 - academic.oup.com
Endothelial dysfunction is involved in the development of atherosclerosis, which precedes
asymptomatic structural vascular alterations as well as clinical manifestations of …

The assessment of endothelial function: from research into clinical practice

AJ Flammer, T Anderson, DS Celermajer, MA Creager… - Circulation, 2012 - Am Heart Assoc
The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

Physiological diagnostic criteria for vascular failure

A Tanaka, H Tomiyama, T Maruhashi, Y Matsuzawa… - …, 2018 - Am Heart Assoc
Briefly, measurement of flow-mediated vasodilation (FMD) of the brachial artery has been
used for the assessment of endothelial function in humans. 14, 15 This technique measures …

Aging and vascular endothelial function in humans

DR Seals, KL Jablonski, AJ Donato - Clinical science, 2011 - portlandpress.com
Advancing age is the major risk factor for the development of CVD (cardiovascular
diseases). This is attributable, in part, to the development of vascular endothelial …

[HTML][HTML] Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study

S Velmurugan, JM Gan, KS Rathod… - The American journal of …, 2016 - Elsevier
Background: The beneficial cardiovascular effects of vegetables may be underpinned by
their high inorganic nitrate content. Objective: We sought to examine the effects of a 6-wk …

Shear stress mediates endothelial adaptations to exercise training in humans

TM Tinken, DHJ Thijssen, N Hopkins, EA Dawson… - …, 2010 - Am Heart Assoc
Although episodic changes in shear stress have been proposed as the mechanism
responsible for the effects of exercise training on the vasculature, this hypothesis has not …

Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation

J Lekakis, P Abraham, A Balbarini… - European Journal …, 2011 - journals.sagepub.com
The endothelium holds a pivotal role in cardiovascular health and disease. Assessment of
its function was until recently limited to experimental designs due to its location. The advent …

Assessment of atherosclerosis: the role of flow-mediated dilatation

M Charakida, S Masi, TF Lüscher… - European heart …, 2010 - academic.oup.com
Evidence suggests that endothelial dysfunction is on the causal pathway for both
atherogenesis and destabilization of established plaques. In this review, the role of flow …

Fruit polyphenols and CVD risk: a review of human intervention studies

MFF Chong, R Macdonald, JA Lovegrove - British journal of nutrition, 2010 - cambridge.org
Epidemiological evidence suggests that polyphenols may, in part, explain the
cardioprotective properties of fruits. This review aims to summarise the evidence for the …

Non-invasive vascular function tests: their pathophysiological background and clinical application

H Tomiyama, A Yamashina - Circulation Journal, 2010 - jstage.jst.go.jp
The arterial tree can be simply classified into 3 compartments: elastic arteries, muscular
arteries, and arterioles. Among the most important functions of the arterial tree are (1) …