[HTML][HTML] Tryptophan metabolism in depression: a narrative review with a focus on serotonin and kynurenine pathways

AS Correia, N Vale - International journal of molecular sciences, 2022 - mdpi.com
Depression is a common and serious disorder, characterized by symptoms like anhedonia,
lack of energy, sad mood, low appetite, and sleep disturbances. This disease is very …

[HTML][HTML] Mingmu Xiaoyao granules regulate the PI3K/Akt/mTOR signaling pathway to reduce anxiety and depression and reverse retinal abnormalities in rats

Q Ma, J Zhou, Z Yang, Y Xue, X Xie, T Li… - Frontiers in …, 2022 - frontiersin.org
Objective: To investigate the effects of Mingmu Xiaoyao granules (MMXY) on the
morphology and function of the retina and the mechanism of PI3K/Akt/mTOR pathway …

Hirami lemon (Citrus reticulata var. depressa) modulates the gut–brain axis in a chronic mild stress-induced depression mouse model

PH Tsai, PC Wu, HR Li, KJS Kumar, SY Wang - Food & Function, 2023 - pubs.rsc.org
Citrus reticulata var. depressa, commonly known as Hirami lemon, is a native citrus species
found in Taiwan and Okinawa islands of Japan. While several Citrus species are known to …

Cardamom oil ameliorates behavioral and neuropathological disorders in a rat model of depression induced by reserpine

AA Abdel-Rasoul, NA Saleh, EN Hosny… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Depression is a public health problem. Despite the
availability of treatment options, its prevalence is increasing. A high rate of treatment failure …

[HTML][HTML] Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS-induced depression-like behaviors through downregulation of α2δ-1

C Jiang, C Wang, W Qu, Y Wang, H Wang, X Wei… - Heliyon, 2023 - cell.com
Depression is a complex and prevalent mental illness. Cherry leaf is a traditional Chinese
herbal medicine, which has confirmed to exert a certain antidepressant effect, but its …

Date palm spathe extract reverses chronic stress‐induced changes in dendritic arborization in the amygdala and impairment of hippocampal long‐term potentiation

M Hadipour, GH Meftahi, GP Jahromi - Synapse, 2023 - Wiley Online Library
Chronic restraint stress induces anxiety‐like behaviors and emotional abnormalities via an
alteration of synaptic remodeling in the amygdala and the hippocampus. Given that the date …

Unveiling the Hepatoprotective and Ameliorative Potential of Natural Products in Paracetamol Overdose

HH Elbalakousy, HF Mohamed… - Journal of Medical …, 2023 - journals.ekb.eg
Paracetamol (Acetaminophen; N-acetyl-P-aminophenol) is a broadly used analgesic and
antipyretic prescription that can have fatal side effects when used in high dosages …

Antidepressant and Anxiolytic Potentials of the Chewing Stick, Salvadora persica

R Vasudevan, G Kandasamy… - Journal of Tropical …, 2023 - Wiley Online Library
Purpose and Objectives. The quest for psychoactive plants possessing therapeutic potential
has evolved emerging interest. Salvadora persica (Sp), belonging to the Salvadoraceae …

Synergistic effects of melatonin and hydrogen sulfide in alleviating cognitive decline and BDNF dysregulation in a rat model of depression

B Samir, F Nada, EA Meriam, M Lamtai… - Egyptian Journal of …, 2024 - Taylor & Francis
This research aimed to investigate the possible anti-amnesic effects of a combined therapy
involving melatonin and H2S in a rat model displaying Depressive-Like Behaviors caused …

β-Asarone Promotes Autophagy by Inhibiting the PI3K/Akt/mTOR Pathway in a Rat Model of Depression in Parkinson's Disease

Z Wang, N Wang, Q Zhang, J Kang, Y Fang, B Ning… - 2022 - researchsquare.com
Depression in Parkinson's disease (DPD) is a major non-motor symptom of Parkinson's
disease (PD), and is accompanied by monoamine neurotransmitter degradation in DPD rats …