Muscle–organ crosstalk: the emerging roles of myokines

MCK Severinsen, BK Pedersen - Endocrine reviews, 2020 - academic.oup.com
Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

Anti‐inflammatory effects of exercise: role in diabetes and cardiovascular disease

BK Pedersen - European journal of clinical investigation, 2017 - Wiley Online Library
Background Persistent inflammation is involved in the pathogenesis of chronic diseases
such as type 2 diabetes mellitus (T2 DM) and cardiovascular disease (CVD). Aims The aim …

Resistance training reduces metabolic syndrome and inflammatory markers in older women: a randomized controlled trial: 老年女性抗阻训练可减少代谢综合征以及 …

CM Tomeleri, MF Souza, RC Burini… - Journal of …, 2018 - Wiley Online Library
摘要背景这项研究在老年女性中分析了不进行饮食干预的为期12 周的抗阻训练(resistance
training, RT) 项目对代谢综合征(metabolic syndrome, MetS) 组份以及炎症生物标志物的影响 …

Exercise as medicine–evidence for prescribing exercise as therapy in 26 different chronic diseases

BK Pedersen, B Saltin - … journal of medicine & science in sports, 2015 - Wiley Online Library
This review provides the reader with the up‐to‐date evidence‐based basis for prescribing
exercise as medicine in the treatment of 26 different diseases: psychiatric diseases …

Exercise mimetics: harnessing the therapeutic effects of physical activity

C Gubert, AJ Hannan - Nature Reviews Drug Discovery, 2021 - nature.com
Exercise mimetics are a proposed class of therapeutics that specifically mimic or enhance
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …

An official European Respiratory Society statement on physical activity in COPD

H Watz, F Pitta, CL Rochester, J Garcia-Aymerich… - 2014 - Eur Respiratory Soc
This European Respiratory Society (ERS) statement provides a comprehensive overview on
physical activity in patients with chronic obstructive pulmonary disease (COPD). A …

Interleukin‐6 myokine signaling in skeletal muscle: a double‐edged sword?

P Muñoz‐Cánoves, C Scheele, BK Pedersen… - The FEBS …, 2013 - Wiley Online Library
Interleukin (IL)‐6 is a cytokine with pleiotropic functions in different tissues and organs.
Skeletal muscle produces and releases significant levels of IL‐6 after prolonged exercise …

Fibroblast growth factor 21—metabolic role in mice and men

H Staiger, M Keuper, L Berti… - Endocrine …, 2017 - academic.oup.com
Since its identification in 2000, the interest of scientists in the hepatokine fibroblast growth
factor (FGF) 21 has tremendously grown, and still remains high, due to a wealth of very …

Inflammaging: The ground for sarcopenia?

Z Liang, T Zhang, H Liu, Z Li, L Peng, C Wang… - Experimental …, 2022 - Elsevier
Sarcopenia is a progressive skeletal muscle disease that occurs most commonly in the
elderly population, contributing to increased costs and hospitalization. Exercise and …

Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia

G Biolo, T Cederholm, M Muscaritoli - Clinical nutrition, 2014 - Elsevier
Skeletal muscle is the most abundant body tissue accounting for many physiological
functions. However, muscle mass and functions are not routinely assessed. Sarcopenia is …