Background Psychomotor agitation is associated with different psychiatric conditions and
represents an important issue in psychiatry. Current recommendations on agitation in …

Since the previous publication of Canadian Network for Mood and Anxiety Treatments
(CANMAT) guidelines in 1997, there has been a substantial increase in evidence‐based …

OBJECTIVE: There is a major unmet need for effective options in the treatment of bipolar
depression. METHOD: Five hundred forty-two outpatients with bipolar I (N= 360) or II (N …

The Canadian Network for Mood and Anxiety Treatments (CANMAT) published guidelines
for the management of bipolar disorder in 2005, with a 2007 update. This second update, in …

These updated guidelines are based on a first edition that was published in 2003, and have
been edited and updated with the available scientific evidence until end of 2008. Their …

Objective: To evaluate the efficacy and tolerability of quetiapine monotherapy versus
placebo for the treatment of mania associated with bipolar disorder. Method: In an …

In this chapter we review research on the diagnosis, course, etiology, and pharmacological
and psychosocial treatment of bipolar disorder (BD). BD is a highly recurrent and severe …

OBJECTIVE: In a placebo-controlled, double-blind study, the authors investigated the
efficacy and safety of olanzapine as monotherapy in relapse prevention in bipolar I disorder …

Background: A panel consisting of academic psychiatrists and pharmacist administrators of
the Texas Department of State Health Services (formerly Texas Department of Mental Health …

Objective: Quetiapine, combined with lithium or divalproex, demonstrates efficacy in the
maintenance treatment of bipolar I disorder. This study investigated the efficacy and safety of …