[HTML][HTML] In-depth analysis of the chemical composition, pharmacological effects, pharmacokinetics, and patent history of mangiferin

M Kaurav, J Kanoujia, M Gupta, P Goyal, S Pant… - Phytomedicine Plus, 2023 - Elsevier
Abstract Introduction Mangiferin (2-D-glucopyranosyl-1, 3, 6, 7-tetrahydroxy-9H-xanthen-9-
one) is extracted from different part of plants such seed, peel, and kernels of mango …

Mangiferin: a natural miracle bioactive compound against lifestyle related disorders

M Imran, MS Arshad, MS Butt, JH Kwon… - Lipids in health and …, 2017 - Springer
The current review article is an attempt to explain the therapeutic potential of mangiferin, a
bioactive compound of the mango, against lifestyle-related disorders. Mangiferin (2-β-D …

Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease

Y Yang, J Chen, Q Gao, X Shan, J Wang, Z Lv - Toxicology, 2020 - Elsevier
Ginkgolide B (GB), a main constituent of Ginkgo biloba extracts, reduces hepatic lipid
accumulation and ameliorates nonalcoholic fatty liver disease (NAFLD) in obese mice, but …

Mangiferin: An effective therapeutic agent against several disorders

S Du, H Liu, T Lei, X Xie, H Wang… - Molecular …, 2018 - spandidos-publications.com
Abstract Mangiferin (1, 3, 6, 7‑tetrahydroxyxanthone‑C2‑β‑D‑glucoside) is a bioactive
ingredient predominantly isolated from the mango tree, with potent antioxidant activity and …

Mangiferin: A xanthonoid with multipotent anti‐inflammatory potential

S Saha, P Sadhukhan, PC Sil - Biofactors, 2016 - Wiley Online Library
Over the last era, small molecules sourced from different plants have gained attention for
their varied and long‐term medicinal benefits. Their advantageous therapeutic effects in …

Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats

S Li, F Meng, X Liao, Y Wang, Z Sun, F Guo, X Li… - PLoS …, 2014 - journals.plos.org
Background Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent liver
diseases around the world, and is closely associated with obesity, diabetes, and insulin …

Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling …

H Li, J Huang, B Yang, T Xiang, X Yin, W Peng… - Toxicology and applied …, 2013 - Elsevier
Although mangiferin which is a naturally occurring glucosylxanthone has exhibited
promising anticancer activities, the detailed molecular mechanism of mangiferin on cancers …

Natural alkaloid and polyphenol compounds targeting lipid metabolism: Treatment implications in metabolic diseases

C Cheng, Z Li, X Zhao, C Liao, J Quan, AM Bode… - European journal of …, 2020 - Elsevier
Once the balance between lipid anabolism and catabolism is broken, metabolic disorder will
occur in the organism and finally lead to metabolic diseases, such as nonalcoholic fatty liver …

Mangiferin improves hepatic lipid metabolism mainly through its metabolite-norathyriol by modulating SIRT-1/AMPK/SREBP-1c signaling

J Li, M Liu, H Yu, W Wang, L Han, Q Chen… - Frontiers in …, 2018 - frontiersin.org
Objective: Mangiferin (MGF) is a natural xanthone, with regulation effect on lipid metabolism.
However, the molecular mechanism remains unclear. We purposed after oral administration …

Modulation of diabetes and dyslipidemia in diabetic insulin-resistant rats by mangiferin: role of adiponectin and TNF-α

S Saleh, N El-Maraghy, E Reda… - Anais da Academia …, 2014 - SciELO Brasil
Mangiferin, present in Mangifera indica bark, was reported to produce hypoglycemic and
antidiabetic activity in an animal model of genetic type 2 diabetes and in streptozotocin …