BACKGROUND Within the antral follicle, the oocyte is reliant on metabolic support from its
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …

The ovary, the female gonad, serves as the source for the germ cells as well as the major
supplier of steroid sex hormones. During embryonic development, the primordial germ cells …

Ovulation is the appropriately timed release of a mature, developmentally competent oocyte
from the ovary into the oviduct, where fertilization occurs. Importantly, ovulation is tightly …

The global infertility rate has been declining from year to year. PCOS is one of the treatable
accountable causes contributing to anovulatory infertility. Nevertheless, the success rate of …

In vitro maturation (IVM) offers significant benefits for human infertility treatment and animal
breeding, but this potential is yet to be fully realised due to reduced oocyte developmental …

Reproductive aging is associated with ovulatory defects. Age‐related ovarian fibrosis
partially contributes to this phenotype as short‐term treatment with anti‐fibrotic compounds …

The chondroitin sulfate proteoglycan versican is important for embryonic development and
several human disorders. The versican V1 splice isoform is widely expressed and cleaved …

Human placental mesenchymal stem cells (hPMSCs) have the ability to release cytokines
and to differentiate into the three germ layers. To date, the relevance of hPMSCs for the …

Ovulation is a cyclical biological rupture event fundamental to fertilisation and endocrine
function. During this process, the somatic support cells that surround the germ cell undergo …

To study the relationship between the expression of 10 selected genes in cumulus cells and
the corresponding oocyte development competence, and the effect of patient age and body …